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竖脊肌平面阻滞与多模式疼痛管理治疗创伤性肋骨骨折的比较:一项匹配队列研究。

Comparison of Erector Spinae Plane Blocks Versus Multimodal Pain Management for Traumatic Rib Fractures: A Matched Cohort Study.

机构信息

Division of Trauma and Acute Care Surgery, Department of Surgery, East Carolina University, Greenville, North Carolina.

University of Texas Southwestern Medical School, Dallas, Texas.

出版信息

J Surg Res. 2024 Feb;294:122-127. doi: 10.1016/j.jss.2023.09.068. Epub 2023 Oct 20.

Abstract

INTRODUCTION

Erector spinae plane blocks (ESPBs) are frequently utilized when treating patients with multiple rib fractures. While previous work has demonstrated the efficacy of ESPB as an adequate method of pain control, there has been no work comparing a continuous ESPB to "best practice" multimodal pain control. We hypothesize that a continuous ESPB catheter combined with a multimodal pain regimen may be associated with a decrease in opioid requirements when compared to a multimodal pain regimen alone.

METHODS

This was a retrospective observational cohort study at a level 1 trauma center from September 2016 through September 2021. Inclusion criteria included patients 18 y or older with at least three unilateral rib fractures who were not mechanically ventilated during admission. The primary outcome was the total morphine equivalents utilized throughout the index admission.

RESULTS

A total of 142 patients were included in this study, 71 in each cohort. Patients included had a mean age of 52.5 y, and 18% were female. Demographic data including injury severity score, total number of rib fractures, and length of stay were similar. While there was a trend toward a decrease in morphine equivalents in the patient cohort undergoing ESPB catheter placement, this was not found to be statistically significant (284.3 ± 244.8 versus 412.6 ± 622.2, P = 0.5).

CONCLUSIONS

While ESPB catheters are frequently utilized for analgesia in the setting of multiple rib fractures, there was no decrease in total opioid usage when compared with patients who were managed with a multimodal pain regimen alone. Further assessment comparing ESPB catheters to best practice multimodal pain control regimens through a prospective, multicenter trial is required to further validate these findings.

摘要

简介

竖脊肌平面阻滞(ESPB)常用于治疗多发性肋骨骨折患者。虽然之前的研究已经证明了 ESPB 作为一种有效的疼痛控制方法的疗效,但还没有比较连续 ESPB 与“最佳实践”多模式疼痛控制的研究。我们假设,与单独使用多模式疼痛方案相比,连续 ESPB 导管加用多模式疼痛方案可能与减少阿片类药物需求有关。

方法

这是 2016 年 9 月至 2021 年 9 月在一级创伤中心进行的回顾性观察队列研究。纳入标准包括年龄 18 岁或以上、至少有 3 处单侧肋骨骨折且住院期间未机械通气的患者。主要结局指标是整个指数住院期间使用的总吗啡等效物。

结果

本研究共纳入 142 例患者,每组 71 例。患者的平均年龄为 52.5 岁,18%为女性。包括损伤严重程度评分、肋骨骨折总数和住院时间在内的人口统计学数据相似。虽然接受 ESPB 导管置管的患者组吗啡等效物呈下降趋势,但无统计学意义(284.3 ± 244.8 与 412.6 ± 622.2,P = 0.5)。

结论

虽然 ESPB 导管常用于多发性肋骨骨折的镇痛,但与单独使用多模式疼痛方案的患者相比,总阿片类药物用量并没有减少。需要通过前瞻性、多中心试验进一步评估 ESPB 导管与最佳实践多模式疼痛控制方案的比较,以进一步验证这些发现。

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