Nanobiosensors Lab, Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran, Tehran 1439817435, Iran.
Nanobiosensors Lab, Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran, Tehran 1439817435, Iran; Medical Biomaterials Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Int J Biol Macromol. 2024 Jan;254(Pt 1):127577. doi: 10.1016/j.ijbiomac.2023.127577. Epub 2023 Oct 20.
Lactate is a metabolite that holds significant importance in human healthcare, biotechnology, and the food industry. The need for lactate monitoring has led to the development of various devices for measuring lactate concentration. Traditional laboratory methods, which involve extracting blood samples through invasive techniques such as needles, are costly, time-consuming, and require in-person sampling. To overcome these limitations, new technologies for lactate monitoring have emerged. Wearable biosensors are a promising approach that offers non-invasiveness, low cost, and short response times. They can be easily attached to the skin and provide continuous monitoring. In this review, we evaluate different types of wearable biosensors for lactate monitoring using lactate oxidase enzyme as biological recognition element and free enzyme systems.
乳酸是一种在人类健康护理、生物技术和食品工业中具有重要意义的代谢物。乳酸监测的需求促使各种用于测量乳酸浓度的设备得以开发。传统的实验室方法通过针等侵入性技术提取血液样本，这些方法既昂贵又耗时，并且需要现场采样。为了克服这些限制，乳酸监测的新技术已经出现。可穿戴生物传感器是一种很有前途的方法，它具有非侵入性、低成本和短响应时间的特点。它们可以轻松地贴在皮肤上，并提供连续监测。在这篇综述中，我们评估了使用乳酸氧化酶作为生物识别元件和游离酶系统的不同类型的可穿戴生物传感器用于乳酸监测。
