McGregor K H, Hainsworth R, Ford R
Q J Exp Physiol. 1986 Oct;71(4):577-87. doi: 10.1113/expphysiol.1986.sp003018.
In dogs anaesthetized with chloralose we determined the reflex responses of the blood vessels in the vascularly isolated hind limb to injection of veratridine into the aortic root. The presence of a cannula tied in the ascending aorta ensured that responses were due to stimulation of nerves only in the region perfused by the coronary arteries. Injections of veratridine resulted in transient decreases in vascular resistance and in venous resistance in a perfused cutaneous vein. The responses were reduced when carotid perfusion pressure was elevated. The afferent pathway for the reflex lay in the vagus nerves and the efferent pathway to the limb was in the sciatic and femoral nerves, but the vasodilatation was shown to be predominantly non-cholinergic.
在用氯醛糖麻醉的狗身上，我们测定了血管分离的后肢血管对向主动脉根部注射藜芦碱的反射反应。在升主动脉处结扎插管可确保反应仅由冠状动脉灌注区域的神经刺激引起。注射藜芦碱会导致灌注的皮静脉血管阻力和静脉阻力短暂降低。当颈动脉灌注压升高时，反应会减弱。反射的传入途径位于迷走神经中，而到肢体的传出途径位于坐骨神经和股神经中，但血管舒张主要显示为非胆碱能的。
