Challenger S, McGregor K H, Hainsworth R
Q J Exp Physiol. 1987 Jul;72(3):271-83. doi: 10.1113/expphysiol.1987.sp003074.
In dogs anaesthetized with chloralose, cardiac receptors were stimulated by increases in left ventricular systolic pressure effected by changes in aortic root pressure. Left atrial and carotid sinus pressures were controlled. A large step increase in ventricular pressure resulted in transient decreases in heart rate, systemic arterial perfusion pressure and perfusion pressure to a vascularly isolated hind limb. The magnitudes of these responses were about three-quarters of those to either a large change in carotid sinus pressure or aortic root injection of 20 micrograms veratridine. Steady-state responses were smaller. There was no significant change in perfusion pressure to a perfused cutaneous vein. Graded changes in ventricular systolic pressure showed that the most sensitive pressure range was between 20 and 24 kPa. These results indicate that changes in left ventricular pressure result in significant vasodilation in the hind limb and in other regions and that responses are obtained when the pressure is moderately elevated.
在用氯醛糖麻醉的狗身上，通过改变主动脉根部压力来增加左心室收缩压，从而刺激心脏感受器。左心房和颈动脉窦压力得到控制。心室压力大幅阶跃增加导致心率、体循环动脉灌注压和血管隔离后肢的灌注压短暂下降。这些反应的幅度约为颈动脉窦压力大幅变化或主动脉根部注射20微克藜芦碱时反应幅度的四分之三。稳态反应较小。灌注的皮肤静脉的灌注压没有显著变化。心室收缩压的分级变化表明，最敏感的压力范围在20至24千帕之间。这些结果表明，左心室压力的变化会导致后肢和其他区域显著的血管舒张，并且当压力适度升高时会出现反应。
