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代谢与减重外科学术认证和质量改进计划:减重手术风险/获益计算器:1 年并存疾病缓解率。

Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program: Bariatric Surgical Risk/Benefit Calculator: 1-year comorbidity remission.

机构信息

American College of Surgeons, Chicago, Illinois.

American College of Surgeons, Chicago, Illinois.

出版信息

Surg Obes Relat Dis. 2024 Mar;20(3):275-282. doi: 10.1016/j.soard.2023.09.020. Epub 2023 Sep 26.

Abstract

BACKGROUND

Clinical calculators can provide patient-personalized estimates of treatment risks and health outcomes. The American College of Surgeons Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) set out to create a publicly available tool to assess both short-term postoperative risk and long-term benefits for prospective adult patients eligible for 1 of 4 primary bariatric procedures. The calculator is comprised of multiple prediction elements: (1) 30-day postoperative risk, (2) 1-year body mass index projections, and (3) 1-year comorbidity remission.

OBJECTIVES

To assess the performance of the 1-year comorbidity remission prediction feature of the calculator.

SETTING

Not-for-profit organization clinical data registry.

METHODS

MBSAQIP data across 4.5 years from 240,227 total patients indicating at least 1 comorbidity of interest present preoperatively and who had a 1-year follow-up record documenting their comorbidity status were included. Six models were constructed, stratified by the presence of the respective preoperative comorbidity: hypertension, hyperlipidemia, gastroesophageal reflux disease, sleep apnea, non-insulin-dependent diabetes, and insulin-dependent diabetes. A multinomial logistic regression model was used to predict 1-year remission (total, partial, or no remission) of insulin-dependent diabetes. All other outcomes were binary (yes or no at 1 yr), and ordinary logistic regression models were used.

RESULTS

All models showed adequate discrimination (C statistics ranging from .58 to .68). Plots of observed versus predicted remission (%) showed excellent calibration across all models.

CONCLUSION

All remission models were well calibrated with sufficient discrimination. The MBSAQIP Bariatric Surgical Risk/Benefit Calculator is a publicly available tool intended for integration into clinical practice to enhance patient-clinician discussions and informed consent.

摘要

背景

临床计算器可以为患者提供治疗风险和健康结果的个性化估计。美国外科医师学院代谢和减重手术认证和质量改进计划(MBSAQIP)旨在创建一个公共可用的工具,以评估符合以下 4 种主要减重手术之一的成年患者的短期术后风险和长期获益:(1)30 天术后风险;(2)1 年体重指数预测;(3)1 年合并症缓解。

目的

评估计算器的 1 年合并症缓解预测功能的性能。

设置

非营利组织临床数据注册处。

方法

MBSAQIP 数据来自 4.5 年期间的 240,227 名患者,这些患者至少存在 1 种术前感兴趣的合并症,并且有 1 年的随访记录记录其合并症状态。纳入了 6 种模型,按术前存在的相应合并症分层:高血压、高脂血症、胃食管反流病、睡眠呼吸暂停、非胰岛素依赖型糖尿病和胰岛素依赖型糖尿病。使用多项逻辑回归模型预测胰岛素依赖型糖尿病 1 年缓解(完全、部分或无缓解)。所有其他结果均为二进制(1 年内为是或否),使用普通逻辑回归模型。

结果

所有模型均显示出足够的区分度(C 统计量范围为 0.58 至 0.68)。观察到的与预测缓解率(%)的图显示所有模型均具有良好的校准。

结论

所有缓解模型均具有良好的校准和足够的区分度。MBSAQIP 减重手术风险/获益计算器是一个公共可用的工具,旨在整合到临床实践中,以增强医患讨论和知情同意。

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