在美国和印度的亚洲印度裔人群中2型糖尿病患病率的比较：地理位置有影响吗？
Comparison of the Prevalence of Type 2 Diabetes Mellitus in Asian Indians Living in the United States and India: Does Location Matter?
作者信息
Ganti Akhil A, Shivaswamy Vijay
机构信息
Department of Biological Sciences, Millard North High School, Omaha, NE, USA.
Division of Diabetes, Endocrinology and Metabolism, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
出版信息
Indian J Endocrinol Metab. 2023 Jul-Aug;27(4):315-318. doi: 10.4103/ijem.ijem_284_22. Epub 2023 Jun 30.
INTRODUCTION
Type 2 diabetes mellitus (T2DM) has affected many people worldwide. One population that is greatly affected by T2DM is the Asian Indian population. The relative effects of genetics and environment on the development of diabetes in adults are not completely understood.
OBJECTIVES
We conducted an analysis to determine if location, through the environment and different diets, affects T2DM inheritance in Asian Indians. We hypothesised that the prevalence of T2DM depended on location.
MATERIALS AND METHODS
We analysed previously collected data on T2DM in the individual states of India and the U.S. and used this information to compare the prevalence of T2DM in Asian Indians living in these two countries.
RESULTS
A total of 1,117,465,226 individuals were surveyed in India. Of these, 108,295,674 individuals had T2DM. Similarly, of the 1,704,846 individuals in the US, 298,107 had T2DM. The prevalence of T2DM was 17.49% in Asian Indians living in the US compared to 9.69% for Indians living in India ( < 0.00001). In individuals with similar genetic backgrounds, environmental factors significantly influence the development of T2DM.
引言
2型糖尿病（T2DM）已影响全球众多人群。受T2DM影响极大的人群之一是亚洲印度人群体。遗传学和环境对成年人糖尿病发病的相对影响尚未完全明确。
目的
我们进行了一项分析，以确定地理位置，通过环境和不同饮食，是否会影响亚洲印度人的T2DM遗传。我们假设T2DM的患病率取决于地理位置。
材料与方法
我们分析了先前在印度各邦和美国收集的关于T2DM的数据，并利用这些信息比较了生活在这两个国家的亚洲印度人中T2DM的患病率。
结果
在印度共调查了1,117,465,226人。其中，108,295,674人患有T2DM。同样，在美国的1,704,846人中，298,107人患有T2DM。生活在美国的亚洲印度人中T2DM的患病率为17.49%，而生活在印度的印度人患病率为9.69%（<0.00001）。在具有相似遗传背景的个体中，环境因素对T2DM的发病有显著影响。
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