Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada.
Rehabilitation Research Program, GF Strong Rehabilitation Centre, Vancouver, BC, Canada.
Neural Plast. 2023 Oct 13;2023:2403175. doi: 10.1155/2023/2403175. eCollection 2023.
Twenty individuals in the chronic stage of stroke walked: (1) at their normal pace, (2) slower than normal, and (3) as fast as possible. Functional near-infrared spectroscopy was used to assess bilateral prefrontal, premotor, sensorimotor, and posterior parietal cortices during walking.
No significant differences in laterality were observed between walking speeds. The ipsilesional prefrontal cortex was overall more active than the contralesional prefrontal cortex. Premotor and posterior parietal cortex activity were larger during slow and fast walking compared to normal-paced walking with no differences between slow and fast walking. Greater increases in brain activation in the ipsilesional prefrontal cortex during fast compared to normal-paced walking related to greater gait speed modulation.
Brain activation is not linearly related to gait speed. Ipsilesional prefrontal cortex, bilateral premotor, and bilateral posterior parietal cortices are important areas for gait speed modulation and could be an area of interest for neurostimulation.
20 名处于中风慢性期的个体进行了以下三种行走方式：（1）正常步速，（2）慢于正常步速，（3）尽可能快。在行走过程中，使用功能性近红外光谱技术评估双侧前额叶、运动前区、感觉运动区和顶后皮质。
行走速度之间没有观察到明显的偏侧性差异。与对侧前额叶皮质相比，患侧前额叶皮质总体上更为活跃。与正常步速相比，在慢步和快步行走时，运动前区和顶后区的活动更大，而慢步和快步行走之间没有差异。与正常步速相比，快步行走时患侧前额叶皮质的脑激活增加更大，与步态速度调节的增加有关。
脑激活与步态速度不成线性关系。患侧前额叶皮质、双侧运动前区和双侧顶后皮质是步态速度调节的重要区域，可能是神经刺激的关注区域。
