Gyanchandani Ankita, Shukla Samarth, Vagha Sunita, Acharya Sourya, Saboo Keyur
Department of Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, IND.
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, IND.
Cureus. 2023 Sep 20;15(9):e45630. doi: 10.7759/cureus.45630. eCollection 2023 Sep.
Germ cell tumors usually occur in the gonads. Extragonadal germ cell tumors (EGCTs) are uncommon, and the head and neck region is a rare primary location. In this region, endodermal sinus tumors are relatively uncommon; they are typically recorded alongside teratomas and infrequently by themselves. When an endodermal sinus tumor arises in the neck, it can present with unique clinical and radiographic features and can be challenging to diagnose and manage. We report the peculiar case of a 25-year-old young adult who was suffering from a painful left-sided neck swelling for a year. Fine needle aspiration cytology (FNAC) of neck mass was performed and the cytomorphological features were suggestive of germ cell tumor. After the diagnosis, the patient received chemotherapy and was posted for wide local excision of the tumor. On microscopic examination, the tumor mass showed histopathological features suggestive of an endodermal sinus tumor.
生殖细胞肿瘤通常发生于性腺。性腺外生殖细胞肿瘤（EGCTs）并不常见，头颈部是其罕见的原发部位。在该区域，内胚窦瘤相对少见；它们通常与畸胎瘤一起记录，单独记录的情况很少。当内胚窦瘤发生于颈部时，可表现出独特的临床和影像学特征，诊断和治疗具有挑战性。我们报告了一例特殊病例，一名25岁的年轻成人左侧颈部疼痛性肿胀长达一年。对颈部肿块进行了细针穿刺细胞学检查（FNAC），细胞形态学特征提示为生殖细胞肿瘤。诊断后，患者接受了化疗，并准备进行肿瘤的广泛局部切除。显微镜检查显示，肿瘤块具有提示内胚窦瘤的组织病理学特征。
