Boutas Ioannis, Kontogeorgi Adamantia, Koufopoulos Nektarios I, Pouliakis Abraham, Dimitrakakis Constantine, Dimas Dionysios T, Sitara Kyparissia, Kalantaridou Sophia, Durmusoglu Fatih
Breast Unit, Rea Maternity Hospital, Athens, GRC.
Third Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Athens, GRC.
Cureus. 2023 Sep 20;15(9):e45597. doi: 10.7759/cureus.45597. eCollection 2023 Sep.
Higher mammographic breast density in premenopausal and postmenopausal women is related to a higher breast cancer risk. In this review, we analyze the correlation between estrogen, progesterone, and mammographic density in postmenopausal women and clarify whether these findings are consistent across different types of mammographic breast density. We extracted data concerning mammographic density increases in the populations treated with estrogen-only hormone replacement therapy and those treated with estrogen and progestin hormone replacement therapy. Postmenopausal women treated with estrogen and progesterone regimens had a statistically significant lesser mammographic density increase than estrogen-only hormone replacement therapy regimens.
绝经前和绝经后女性较高的乳腺钼靶密度与较高的乳腺癌风险相关。在本综述中，我们分析了绝经后女性雌激素、孕激素与乳腺钼靶密度之间的相关性，并阐明这些发现在不同类型的乳腺钼靶密度中是否一致。我们提取了接受单纯雌激素激素替代疗法和接受雌激素加孕激素激素替代疗法人群中乳腺钼靶密度增加的数据。接受雌激素和孕激素治疗方案的绝经后女性，其乳腺钼靶密度增加在统计学上显著低于单纯雌激素激素替代疗法方案。
