Roshani Delband, Setayeshi Saeed
Department of Energy Engineering and Physics, Amirkabir University of Technology, Tehran, Iran.
J Biomed Phys Eng. 2023 Oct 1;13(5):471-476. doi: 10.31661/jbpe.v0i0.2009-1190. eCollection 2023 Oct.
Positron Emission Mammography (PEM) is a nuclear medicine imaging tool, playing a significant role in the diagnosis of patients with breast cancer. These days, many research has been done in order to improve the performance of this system.
This study aims to propose a new method for optimizing the size of axial Field of View (FOV) in PEMs and improving the performance of the systems.
In this analytical study, a conventional Inveon PET is simulated using GATE in order to validate the simulation. For this simulation, the mean relative difference is 2.91%, showing the precision and correction of simulation and consequently it is benchmarked. In the next step, for design of the new optimized detector, several validated simulations are performed in order to find the best geometry.
The best result is obtained with the axial FOV of 101.7 mm. It has 1.6×1.6×15 mm lutetium yttrium orthosilicate (LYSO) crystals. The detector consists of 6 block rings with 30 detector blocks in each ring. In this paper, the performance of the scanner is improved and the geometry is optimized. Sensitivity and scatter fraction of the designed scanner are 4.65% and 21.2%, respectively, also noise equivalent count rate (NECR) is 105.442 kcps.
The results showed 1 up to 3% improvement in the sensitivity of this new detector compared with different PEMs.
正电子发射乳腺断层成像（PEM）是一种核医学成像工具，在乳腺癌患者的诊断中发挥着重要作用。如今，为了提高该系统的性能已经开展了许多研究。
本研究旨在提出一种优化PEM轴向视野（FOV）大小并提高系统性能的新方法。
在这项分析研究中，使用GATE对传统的Inveon PET进行模拟以验证模拟结果。对于此模拟，平均相对差异为2.91%，表明模拟的精度和正确性，因此将其作为基准。下一步，为设计新的优化探测器，进行了多次经过验证的模拟以找到最佳几何结构。
轴向视野为101.7毫米时获得了最佳结果。它具有1.6×1.6×15毫米的硅酸钇镥（LYSO）晶体。探测器由6个块环组成，每个环中有30个探测器块。本文提高了扫描仪的性能并优化了几何结构。设计的扫描仪的灵敏度和散射分数分别为4.65%和21.2%，噪声等效计数率（NECR）为105.442千计数每秒。
结果表明，与不同的PEM相比，这种新探测器的灵敏度提高了1%至3%。
