Soh Bing Wei Thaddeus, Prendergast Sophie Catherine, Burke Louise, O'Connor Cormac T, Ullah Ihsan, O'Brien Julie M, Hinchion John A, Arnous Samer, Kiernan Thomas J
Department of Cardiology, University Hospital Limerick, Limerick, Ireland.
Department of Histopathology, Cork University Hospital, Cork, Ireland.
JACC Case Rep. 2023 Sep 15;24:102027. doi: 10.1016/j.jaccas.2023.102027. eCollection 2023 Oct 18.
IgG4-related disease (IgG4-RD) is a new clinical entity characterized by lymphoplasmacytic lesions rich in IgG4-positive plasma cells. Myocardial involvement is extremely rare and not a typical cardiovascular manifestation of IgG4-RD. We report a rare case of IgG4-RD-associated myocardial mass causing severe aortic incompetence, successfully treated with surgery and corticosteroids. ().
IgG4相关性疾病（IgG4-RD）是一种新的临床实体，其特征为富含IgG4阳性浆细胞的淋巴浆细胞性病变。心肌受累极为罕见，并非IgG4-RD的典型心血管表现。我们报告一例罕见的IgG4-RD相关心肌肿物导致严重主动脉瓣关闭不全的病例，通过手术和皮质类固醇成功治愈。（）
