在既往接受过青光眼引流装置植入术（GATT）的眼中，Ozurdex®注射后因短暂性低眼压导致的反流性前房积血
Reflux hyphema from transient hypotony after Ozurdex® in eyes with prior GATT.
作者信息
Tanenbaum Rebecca E, Xiao Jason, Qiu Mary
机构信息
Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, USA.
Pritzker School of Medicine, University of Chicago, Chicago, IL, USA.
出版信息
Am J Ophthalmol Case Rep. 2023 Oct 6;32:101939. doi: 10.1016/j.ajoc.2023.101939. eCollection 2023 Dec.
PURPOSE
To report on delayed-onset hyphema following intravitreal injection of dexamethasone implant Ozurdex® in eyes with a history of gonioscopy-assisted transluminal trabeculotomy (GATT).
OBSERVATIONS
We describe two cases of hyphema occurring within one day following Ozurdex® implantation in eyes that had undergone GATT at least one year prior. One case responded well to medical management, while the other required anterior chamber paracentesis for intraocular pressure (IOP) control. Both patients achieved normalization of IOP following resolution of the hyphema, and have not had recurrence.
CONCLUSIONS AND IMPORTANCE
We propose that transient hypotony immediately after Ozurdex® injection may lead to a reflux of blood from the episcleral venous network into the anterior chamber in eyes with prior ab interno trabeculotomy. Glaucoma and retina specialists should be aware of this potential complication to guide follow up and management in the post-injection period for these patients.
目的
报告在有前房角镜辅助小梁切开术（GATT）病史的眼中玻璃体内注射地塞米松植入剂Ozurdex®后发生的迟发性前房积血。
观察结果
我们描述了两例在至少一年前接受过GATT的眼中植入Ozurdex®后一天内发生前房积血的病例。一例对药物治疗反应良好，而另一例需要前房穿刺以控制眼压。两例患者在前房积血消退后眼压均恢复正常，且未复发。
结论与意义
我们认为Ozurdex®注射后立即出现的短暂性低眼压可能导致既往行内路小梁切开术的眼中巩膜静脉网的血液反流至前房。青光眼和视网膜专科医生应意识到这种潜在并发症，以便在这些患者注射后阶段指导随访和治疗。
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