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[双侧丘脑梗死伴异常运动和永久性失忆]

[Bilateral thalamic infarcts with abnormal movements and permanent amnesia].

作者信息

Rondot P, de Recondo J, Davous P, Bathien N, Coignet A

出版信息

Rev Neurol (Paris). 1986;142(4):398-405.

PMID:3787045
Abstract

A 45 year-old woman with mitral valve disease developed bilateral thalamic infarcts presenting as vigilance disorders, with mutism and downwards gaze paralysis during several days, followed by involuntary rhythmic movements over 13 days. These movements affected the four limbs with a rhythm variable with time as alternate or synchronized agonist-antagonist periods. Subsequent examinations demonstrated global, lasting amnesia and a subclinical disorder of vertical ocular movements. Repeat CT scan confirmed the presence of bilateral anterior thalamic infarcts affecting polar and/or paramedian territories. Emphasis is placed on the similarity of the abnormal movements in this case with L-dopa induced involuntary movements.

摘要

一名患有二尖瓣疾病的45岁女性发生双侧丘脑梗死,表现为警觉障碍,数天内出现缄默症和向下凝视麻痹,随后在13天内出现不自主节律性运动。这些运动累及四肢,其节律随时间变化,表现为交替或同步的主动肌 - 拮抗肌活动期。后续检查显示存在全面、持久的失忆以及垂直眼球运动的亚临床障碍。重复CT扫描证实双侧丘脑前梗死灶的存在,累及丘脑极部和/或旁正中区域。本文强调了该病例中异常运动与左旋多巴诱发的不自主运动的相似性。

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