Sun Jinting, Chen Daoming, Qin Chunlan, Liu Rui
Department of Pulmonology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Department of Operating Room, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Support Care Cancer. 2023 Oct 23;31(12):650. doi: 10.1007/s00520-023-08092-9.
This study aimed to evaluate the impact of mind-body exercise (yoga, tai chi, qigong, etc.) on lung cancer.
We performed a literature search of the electronic databases PubMed, Web of Science, Cochrane Library, Embase, CNKI, CBM, WanFang Data, and VIP from their inception to 16 May 2023. The primary outcome was the 6-min walk test (6MWT), while the secondary outcomes were anxiety levels and quality of life (QoL). Two independent reviewers performed the data extraction using a predefined protocol and assessed the risk of bias using the Cochrane risk of bias (ROB) tool for randomized controlled trials, with differences agreed by consensus. Meta-analysis was performed using RevMan 5.4 and Stata 15 software to analyze the extracted data.
This meta-analysis included a total of 11 studies involving 897 patients. The results indicated that compared to the usual care group, lung cancer patients in the mind-body exercise group could increase the 6-min walk distance (5 studies, 346 participants, WMD: 18.83, 95% CI (7.55, 30.10) P = 0.001), reduce anxiety levels (4 studies, 362 participants, SMD: - 1.51, 95% CI (- 1.74, - 1.27), P < 0.05), and enhance the overall quality of life (6 studies, 594 participants, SMD: 0.71, 95% CI (0.10, 1.31), P = 0.02). The overall certainty of the evidence for all outcomes was low; seven studies were judged to be at low risk of bias, and four studies were judged to be at moderate risk of bias.
Mind-body exercise could improve exercise capacity in lung cancer survivors, reduce anxiety, and positively affect overall quality of life.
CRD42023426800.
本研究旨在评估身心锻炼（瑜伽、太极、气功等）对肺癌的影响。
我们对电子数据库PubMed、Web of Science、Cochrane图书馆、Embase、中国知网（CNKI）、中国生物医学文献数据库（CBM）、万方数据和维普资讯进行了文献检索，检索时间从各数据库建库至2023年5月16日。主要结局指标为6分钟步行试验（6MWT），次要结局指标为焦虑水平和生活质量（QoL）。两名独立的审阅者使用预定义的方案进行数据提取，并使用Cochrane偏倚风险（ROB）工具对随机对照试验的偏倚风险进行评估，如有分歧则通过共识解决。使用RevMan 5.4和Stata 15软件进行荟萃分析，以分析提取的数据。
本荟萃分析共纳入11项研究，涉及897例患者。结果表明，与常规护理组相比，身心锻炼组的肺癌患者可以增加6分钟步行距离（5项研究，346名参与者，加权均数差：18.83，95%可信区间（7.55，30.10），P = 0.001），降低焦虑水平（4项研究，362名参与者，标准化均数差：−1.51，95%可信区间（−1.74，−1.27），P < 0.05），并提高总体生活质量（6项研究，594名参与者，标准化均数差：0.71，95%可信区间（0.10，1.31），P = 0.02）。所有结局指标证据的总体确定性较低；7项研究被判定为低偏倚风险，4项研究被判定为中度偏倚风险。
身心锻炼可以提高肺癌幸存者的运动能力，减轻焦虑，并对总体生活质量产生积极影响。
PROSPERO注册号：CRD42023426800。
