Skjødt T, Anker-Møller E, Svendsen J, Jacobsen E B
Rontgenblatter. 1986 Oct;39(10):275-9.
55 rather young patients suspected of dementia were examined via CT to assess the comparative value of various CT examination methods to determine cerebral atrophy. The patients were assessed clinically and classified as normal (24), slightly demented (21) and moderately demented (10). There were no severely demented patients. The parameters measured consisted of several diameters and indexes as well as the volume of the ventricular system and of the subarachnoidal space. The atrophy level was also determined visually. With the exception of the breadth of the third ventricle there was no correlation between internal cerebral atrophy and the level of dementia. Neither the mean breadths of four external sulci nor the volume of the subarachnoidal space (both being representative of external atrophy) showed any significant correlation with the degree of dementia of the patients on the levels 0.005 or 0.025, respectively. However, the results were not better than those obtained by visual assessment of external atrophy. Reasons are discussed why objective measurements do not yield reliable results.
对55名疑似患有痴呆症的相对年轻的患者进行了CT检查,以评估各种CT检查方法在确定脑萎缩方面的比较价值。对这些患者进行了临床评估,并分为正常(24例)、轻度痴呆(21例)和中度痴呆(10例)。没有重度痴呆患者。测量的参数包括几个直径和指数,以及脑室系统和蛛网膜下腔的体积。萎缩程度也通过视觉确定。除第三脑室宽度外,脑内萎缩与痴呆程度之间没有相关性。四个脑沟的平均宽度和蛛网膜下腔的体积(均代表外部萎缩)分别在0.005或0.025水平上与患者的痴呆程度均无显著相关性。然而,结果并不比通过视觉评估外部萎缩得到的结果更好。文中讨论了客观测量不能产生可靠结果的原因。