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由 SARS-CoV-2 感染引起的慢性双侧泪腺炎:一例报告。

Chronic bilateral dacryoadenitis caused by SARS-CoV-2 infection: a case report.

机构信息

Division of Infectious Diseases, Department of Internal Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center, Al Khoud, PO Box 566, Muscat, Sultanate of Oman.

出版信息

J Med Case Rep. 2023 Oct 24;17(1):441. doi: 10.1186/s13256-023-04175-7.

DOI:10.1186/s13256-023-04175-7
PMID:37872576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10594824/
Abstract

BACKGROUND

Dacryoadenitis is inflammation of the lacrimal gland, mainly caused by viral infection. It can also be caused by bacterial pathogens and non-infectious processes such as auto-immune diseases and malignancy. Chronic dacryoadenitis is rarely linked to SARS-CoV-2 infection, with only five reports in the literature.

REPORT

A 26-year-old Arab woman experienced chronic inflammatory dacryoadenitis after a mild SARS-CoV-2 infection, which was successfully treated with oral prednisone.

CONCLUSIONS

Dacryoadenitis can occur due to inflammation caused by either SARS-CoV-2 exposure. The treatment typically involves the administration of steroids, with duration to be decided based on clinical response.

摘要

背景

泪腺炎是泪腺的炎症,主要由病毒感染引起。它也可能由细菌病原体和非传染性过程引起,如自身免疫性疾病和恶性肿瘤。慢性泪腺炎很少与 SARS-CoV-2 感染有关,文献中仅有五例报告。

报告

一名 26 岁的阿拉伯妇女在轻度 SARS-CoV-2 感染后经历了慢性炎症性泪腺炎,口服泼尼松治疗后成功治愈。

结论

SARS-CoV-2 暴露引起的炎症可导致泪腺炎。治疗通常包括使用类固醇,具体持续时间取决于临床反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/888c/10594824/d6b90ab05220/13256_2023_4175_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/888c/10594824/3f20ad61af6a/13256_2023_4175_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/888c/10594824/d6b90ab05220/13256_2023_4175_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/888c/10594824/3f20ad61af6a/13256_2023_4175_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/888c/10594824/d6b90ab05220/13256_2023_4175_Fig2_HTML.jpg

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2
Ocular manifestations of COVID-19.新型冠状病毒肺炎的眼部表现
Ther Adv Ophthalmol. 2022 Apr 12;14:25158414221083374. doi: 10.1177/25158414221083374. eCollection 2022 Jan-Dec.
3
Infectious Dacryoadenitis: A Comprehensive Review.感染性泪腺炎:全面综述
Int Ophthalmol Clin. 2022 Apr 1;62(2):71-86. doi: 10.1097/IIO.0000000000000412.
4
Acute-onset dacryoadenitis following immunisation with mRNA COVID-19 vaccine.接种 mRNA COVID-19 疫苗后急性泪腺炎。
BMJ Case Rep. 2022 Mar 7;15(3):e248441. doi: 10.1136/bcr-2021-248441.
5
COVID-19-Related Chronic Bilateral Dacryoadenitis: A Clinicopathological Study.COVID-19 相关的慢性双侧泪腺炎:一项临床病理研究。
JAMA Ophthalmol. 2022 Apr 1;140(4):312-318. doi: 10.1001/jamaophthalmol.2021.6364.
6
Non-infectious Dacryoadenitis.非传染性泪腺炎。
Surv Ophthalmol. 2022 Mar-Apr;67(2):353-368. doi: 10.1016/j.survophthal.2021.05.011. Epub 2021 May 31.
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Orbital inflammatory disease associated with COVID-19 infection.与 COVID-19 感染相关的眼眶炎性疾病。
J AAPOS. 2021 Aug;25(4):232-234. doi: 10.1016/j.jaapos.2021.04.002. Epub 2021 May 6.
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Orbit. 2022 Oct;41(5):633-636. doi: 10.1080/01676830.2021.1914670. Epub 2021 Apr 19.
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