Department of Ophthalmology, University of Würzburg, Würzburg, Germany.
Artemis Eye Centers of Frankfurt, Hanauer Landstr. 147, 60314, Frankfurt, Germany.
Int Ophthalmol. 2023 Dec;43(12):5071-5078. doi: 10.1007/s10792-023-02910-z. Epub 2023 Oct 24.
To compare two approaches for the implantation of the PRESERFLO microshunt: an anterior approach (A) with a 6-8-mm peritomy and a posterior approach (P) with a 3-mm incision.
We retrospectively analyzed 126 patients who received a PRESERFLO microshunt. We compared intraocular pressure (IOP), surgical time, medication count, and postoperative complications over nine months.
The baseline IOP was similar in A (21.8 ± 8.5 mm Hg) and P (23.9 ± 8.1 mm Hg) (p = 0.08). Surgical duration was significantly shorter in P (10 ± 0.4 min) than in A (26 ± 0.8 min) (p < 0.001). Postoperative IOP levels were comparable in A (10.8 ± 5.9 mm Hg) and P (10.6 ± 4.5 mm Hg) at 30 days (p = 0.62) and throughout the study (all intra-group p-values > 0.08). The preoperative medication count was 3.2 ± 1.3 drops in A and 3.3 ± 1.0 drops in P (p = 0.4). Postoperative values were 0.2 ± 0.6 in A and 0.3 ± 0.7 in P at nine months. There were no significant differences in complications and surgical revisions between groups (p-values > 0.05).
Both techniques achieved satisfactory IOP and medication count reductions and had similar safety profiles, but the posterior incision technique was 2.6 times faster than the anterior incision technique.
比较 PRESERFLO 微分流管植入的两种方法：前入路（A）行 6-8mm 切开，后入路（P）行 3mm 切口。
我们回顾性分析了 126 例接受 PRESERFLO 微分流管植入的患者。我们比较了 9 个月内的眼压（IOP）、手术时间、用药次数和术后并发症。
A 组（21.8±8.5mmHg）和 P 组（23.9±8.1mmHg）的基线 IOP 相似（p=0.08）。P 组的手术时间明显短于 A 组（10±0.4min 比 26±0.8min）（p<0.001）。A 组和 P 组术后 30 天（p=0.62）和整个研究期间（组内所有 p 值均>0.08）的术后 IOP 水平相当。A 组术前用药次数为 3.2±1.3 滴，P 组为 3.3±1.0 滴（p=0.4）。A 组术后 9 个月时为 0.2±0.6 滴，P 组为 0.3±0.7 滴。两组间并发症和手术修订无显著差异（p 值均>0.05）。
两种技术均能达到满意的 IOP 和用药次数减少，且安全性相似，但后入路切口技术比前入路切口技术快 2.6 倍。
