Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Department of Cardiovascular Medicine and Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, The Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Curr Cardiol Rep. 2023 Nov;25(11):1523-1533. doi: 10.1007/s11886-023-01980-w. Epub 2023 Oct 24.
The role of emergent cardiac catheterization after resuscitated out-of-hospital cardiac arrest (OHCA) has evolved based on recent randomized evidence. This review aims to discuss the latest evidence and current indications for emergent coronary angiography (CAG) and mechanical circulatory support (MCS) use following OHCA.
In contrast to previous observational data, recent RCTs evaluating early CAG in resuscitated OHCA patients without ST elevation have uniformly demonstrated a lack of benefit in terms of survival or neurological outcome. There is currently no randomized evidence supporting MCS use specifically in patients with resuscitated OHCA and cardiogenic shock. Urgent CAG should be considered in all patients with ST elevation, recurrent electrical or hemodynamic instability, those who are awake following resuscitated OHCA, and those receiving extracorporeal cardiopulmonary resuscitation (ECPR). Recent evidence suggests that CAG may be safely delayed in hemodynamically stable patients without ST-segment elevation following resuscitated OHCA.
复苏后院外心脏骤停(OHCA)后紧急心导管检查的作用是基于最近的随机证据而演变的。本综述旨在讨论 OHCA 后紧急冠状动脉造影(CAG)和机械循环支持(MCS)使用的最新证据和当前适应证。
与之前的观察性数据相比,最近评估无 ST 段抬高的复苏后 OHCA 患者早期 CAG 的 RCT 均一致表明,在生存或神经结局方面没有获益。目前没有随机证据支持 MCS 在复苏后 OHCA 合并心源性休克的患者中专门使用。所有 ST 段抬高、电或血流动力学再次不稳定、复苏后清醒和接受体外心肺复苏(ECPR)的患者均应考虑紧急 CAG。最近的证据表明,在复苏后 OHCA 无 ST 段抬高且血流动力学稳定的患者中,CAG 可安全延迟。