Gritsaĭ A A, Lichinitser M R, Vyshinskaia G V, Kondrat'eva A P, Aplevich N N
Ter Arkh. 1986;58(9):105-8.
The treatment schedule for disseminated breast carcinoma has been developed. It includes the use of adriamycin (30 mg/m2, days 1, 8, 15), methotrexate (30 mg/m2, day 1), 5-FU (600 mg/m2, day 8), and cyclophosphamide (400 mg/m2, day 15 i. v. by jet injection). A complete response was obtained in 50 to 56% of the patients, with remissions lasting for an appreciable period of time. The use of chemotherapy according to the described schedule combined with radiation of the bones of the pelvis and lumbar part of the spine brought about complete or partial reparation of the osteolytic, osteoblastic and mixed metastatic foci in 76.2% of the patients.
已制定出播散性乳腺癌的治疗方案。该方案包括使用阿霉素（30毫克/平方米，第1、8、15天）、甲氨蝶呤（30毫克/平方米，第1天）、5-氟尿嘧啶（600毫克/平方米，第8天）和环磷酰胺（400毫克/平方米，第15天，静脉推注）。50%至56%的患者获得了完全缓解，缓解期持续了相当长的时间。按照所述方案使用化疗并结合骨盆和腰椎骨的放疗，使76.2%的患者的溶骨性、成骨性和混合性转移灶实现了完全或部分修复。
