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[阿霉素(多柔比星)在播散型乳腺癌患者联合化疗中的应用]

[Adriablastin (doxorubicin) in the combined chemotherapy of patients with disseminated forms of breast cancer].

作者信息

Voznyĭ E K, Besova N S, Kurkina T V, Al'tshtuller Iu B

出版信息

Antibiotiki. 1984 Jun;29(6):463-8.

PMID:6476811
Abstract

A total of 119 patients were treated for disseminated cancer of the mammary gland according to two schemes with the use of adriablastin. It was shown that in the treatment of metastases into the bones adriablastin was the drug of choice. The treatment of such patients with it may be effective. The analgetic action of the drug was noted in 80 per cent of the patients. The roentgenologically observed objective effect of the drug was provided by the doses higher than 300 mg and the treatment period of not less than 4 months. In the treatment of patients with metastases of other localization the schemes with the use of adriablastin had no advantage over the Cooper scheme.

摘要

共有119例乳腺播散性癌患者按照两种使用阿霉素的方案进行治疗。结果表明,在治疗骨转移时,阿霉素是首选药物。用其治疗此类患者可能有效。80%的患者注意到了该药物的止痛作用。高于300毫克的剂量且治疗期不少于4个月可产生该药物在X线检查中观察到的客观效果。在治疗其他部位转移的患者时,使用阿霉素的方案并不比库珀方案更具优势。

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