Hemangioma and Vascular Malformation Center, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 7015, Cincinnati, OH 45229, USA.
Department of Oral and Maxillofacial Surgery-Head and Neck Oncology and Microvascular Reconstruction, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Oral Maxillofac Surg Clin North Am. 2024 Feb;36(1):103-113. doi: 10.1016/j.coms.2023.09.011. Epub 2023 Oct 23.
Vascular anomalies, broadly classified as nonmalignant tumors and malformations, consist of a multitude of disorders that have a wide range of symptoms and complications as well as overlapping clinical, radiologic, and histologic findings. Although usually difficult, distinguishing between nonmalignant vascular tumors and malformations, as well as the precise diagnosis within these distinctions, is critical because prognosis, therapy, and chronicity of care vary greatly. In contrast to normal endothelial turnover in vascular malformations, vascular tumors are characterized by the abnormal proliferation of endothelial cells and aberrant blood vessels.
血管异常广泛地分为非肿瘤性良性肿瘤和畸形，由多种疾病组成，这些疾病具有广泛的症状和并发症，以及重叠的临床、放射学和组织学表现。虽然通常很困难，但区分非肿瘤性血管肿瘤和畸形，以及在这些区别内进行准确诊断非常重要，因为预后、治疗和长期护理的方式差异很大。与血管畸形中正常的内皮细胞更新不同，血管肿瘤的特征是内皮细胞的异常增殖和异常血管。
