Suppr超能文献

接受抗病毒治疗的男男性行为HIV感染者中“检测不到即不具传染性”概念认知情况调查

[Survey on the cognition of the "undetectable equals untransmittable" concept among HIV-infected men who have sex with men receiving antiviral treatment].

作者信息

Zhang K C, Meng X J, Hu T, Luo D, Cao H, Lin Q H, Zou H C

机构信息

Longhua District Centre for Disease Control and Prevention, Shenzhen 518109, China.

Wuxi Prefectural Centre for Disease Control and Prevention, Wuxi 214023, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2023 Oct 10;44(10):1610-1615. doi: 10.3760/cma.j.cn112338-20230424-00264.

Abstract

To explore the cognition of the "undetectable equals untransmittable" ("U=U") concept and associated factors among HIV-infected men who have sex with men (MSM) receiving antiviral treatment (ART) in Shenzhen, and provide evidence for designing promotion and advocacy strategies for the "U=U" concept. We recruited HIV-infected MSM receiving ART using convenient sampling method combined with routine follow-up in Shenzhen through conducting observational survey. The sample size was estimated to be 475. A questionnaire was administered to collect socio-demographic characteristics, sexual behaviors, ART, viral load testing and the cognition towards "U=U" in HIV-infected MSM. Logistic regression was used to access factors associated with acceptance of "U=U". A total of 490 HIV-infected MSM receiving ART were recruited. Of whom, 60.2% (295/490) were aware of "U=U" and 50.6% (248/490) accepted "U=U". Multiple logistic regression showed that participants who had an educational level of college or above (a=1.76,95%: 1.12-2.75) were more likely to accept "U=U". Those who had no local residency (a=0.51,95%: 0.29-0.92), had viral load >0 copies/ml in the last testing (a=0.61,95%: 0.38-0.98) and were unaware of "U=U" (a=0.13, 95%: 0.09-0.21), were less likely to accept "U=U". HIV-infected MSM receiving ART had a low cognition level of "U=U" in Shenzhen. Promotion and advocacy on this concept through healthcare workers should be enhanced in combination with routine follow-up in order to improve their ART adherence and outcome of treatment. Furthermore, developing related guidelines on "U=U" according to the characteristics of HIV-infected individuals is warranted to improve the normalization of promotion and advocacy on "U=U".

摘要

为探讨在深圳接受抗病毒治疗(ART)的男男性行为者(MSM)艾滋病毒感染者对“检测不到即不具传染性”(“U=U”)概念的认知及相关因素,为制定“U=U”概念的推广和倡导策略提供依据。我们采用方便抽样法结合深圳常规随访,招募接受ART的艾滋病毒感染MSM进行观察性调查。样本量估计为475。通过问卷调查收集艾滋病毒感染MSM的社会人口学特征、性行为、ART、病毒载量检测及对“U=U”的认知情况。采用逻辑回归分析与接受“U=U”相关的因素。共招募了490名接受ART的艾滋病毒感染MSM。其中,60.2%(295/490)知晓“U=U”,50.6%(248/490)接受“U=U”。多因素逻辑回归显示,大专及以上文化程度的参与者(α=1.76,95%:1.12 - 2.75)更有可能接受“U=U”。无本地户籍者(α=0.51,95%:0.29 - 0.92)、上次检测病毒载量>0拷贝/ml者(α=0.61,95%:0.38 - 0.98)以及不知晓“U=U”者(α=0.13,95%:0.09 - 0.21)接受“U=U”的可能性较小。深圳接受ART的艾滋病毒感染MSM对“U=U”的认知水平较低。应结合常规随访,加强医护人员对这一概念的推广和倡导,以提高他们的ART依从性和治疗效果。此外,有必要根据艾滋病毒感染者的特点制定“U=U”相关指南,以促进“U=U”推广和倡导的规范化。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验