Department of Bone and Joint Infection, Luoyang Orthopedic-Traumatological Hospital of Henan Provincial, Luoyang, China.
Degree and Graduate Education Luoyang Work Department, Henan University of Traditional Chinese Medicine, Luoyang, China.
J Orthop Surg Res. 2023 Oct 24;18(1):796. doi: 10.1186/s13018-023-04259-6.
To compare the clinical efficacy of vacuum sealing drainage, eggshell-like debridement combined with antibiotic calcium sulphate implantation and conventional debridement combined with antibiotic calcium sulphate implantation in the treatment of calcaneal osteomyelitis.
Sixty-six patients with calcaneal osteomyelitis who were treated in our department between January 2017 and August 2021 were included in this study. Thirty-one patients underwent VSD and eggshell-like debridement combined with antibiotic calcium sulphate implantation. Thirty-five patients underwent conventional debridement combined with antibiotic calcium sulphate implantation. The inflammatory markers, operation time, wound healing time, hospital stay, full weight bearing time after operation, recurrence rate of infection, complications, and American Orthopedic Foot and Ankle Society (AOFAS) scores were compared between the two groups.
The operation time and full weight bearing time after operation of observation group were longer than that of control group. Compared with preoperative results, WBC, ESR, CRP and PCT in both groups were significantly decreased at 14 days after operation, and there was no statistical significance between the two groups. The wound healing time and hospital stay in the observation group were shorter than those in the control group (P < 0.05). There were four patients with aseptic exudation in the observation group and ten patients with aseptic exudation in the control group, and the wounds healed well after multiple dressing changes. Seven patients in the observation group underwent secondary bone grafting due to bone defects, and four patients in the control group received secondary bone grafting due to bone defects. In the observation group, three patients received debridement combined with antibiotic calcium sulphate implantation again due to recurrent infection, compared with seven patients in the control group. One year after operation, the observation group had a better AOFAS scores than the control group, especially in terms of foot function (P < 0.05).
Compared with conventional debridement and antibiotic calcium sulphate implantation, VSD and eggshell-like debridement combined with antibiotic calcium sulphate implantation in the treatment of calcaneal osteomyelitis can shorten the wound healing and hospital stay of patients, reduce postoperative aseptic exudation complications and infection recurrence rate, and better preserve the foot function, which is a simple and effective method.
比较真空密封引流、蛋壳样清创联合抗生素硫酸钙植入与常规清创联合抗生素硫酸钙植入治疗跟骨骨髓炎的临床疗效。
纳入 2017 年 1 月至 2021 年 8 月我科收治的 66 例跟骨骨髓炎患者,其中 31 例行 VSD 及蛋壳样清创联合抗生素硫酸钙植入,35 例行常规清创联合抗生素硫酸钙植入。比较两组患者的炎症标志物、手术时间、创面愈合时间、住院时间、术后完全负重时间、感染复发率、并发症及美国矫形足踝协会(AOFAS)评分。
观察组手术时间及术后完全负重时间长于对照组,与术前比较,两组患者术后 14 天白细胞计数(WBC)、红细胞沉降率(ESR)、C 反应蛋白(CRP)、降钙素原(PCT)均明显降低,两组比较差异无统计学意义;观察组创面愈合时间及住院时间短于对照组(P<0.05)。观察组 4 例出现无菌性渗出,10 例出现无菌性渗出,经多次换药后愈合良好;观察组 7 例因骨缺损行二期植骨,对照组 4 例因骨缺损行二期植骨;观察组因感染复发再次行清创联合抗生素硫酸钙植入 3 例,对照组 7 例。术后 1 年,观察组 AOFAS 评分优于对照组,尤其在足部功能方面(P<0.05)。
与常规清创联合抗生素硫酸钙植入比较,VSD 及蛋壳样清创联合抗生素硫酸钙植入治疗跟骨骨髓炎能缩短患者的创面愈合及住院时间,降低术后无菌性渗出并发症及感染复发率,更好地保留足部功能,是一种简单有效的方法。