Department of Otorhinolaryngology-Head and Neck Surgery, Guro Hospital, Korea University College of Medicine, 08308, Seoul, South Korea.
Upper Airway Chronic Inflammatory Diseases Laboratory, Korea University, College of Medicine, Seoul, South Korea.
J Otolaryngol Head Neck Surg. 2023 Oct 24;52(1):69. doi: 10.1186/s40463-023-00677-y.
Biocompatibility and stability of three-dimensional printed polycaprolactone mesh grafts for nasal surgery are proven in both animal and human models. However, their safety and durability as batten grafts for caudal septal deviation has not been documented. This study was designed to investigate the efficacy and safety of three-dimensional printed polycaprolactone mesh batten graft in septoplasty using the wedge resection technique for the correction of caudal septal deviation.
This retrospective study reviewed the medical records of 20 patients aged ≥ 18 years with caudal septal deviation who underwent septoplasty with wedge resection and three-dimensional printed polycaprolactone mesh graft from a tertiary medical center in South Korea, between December 1, 2019 and May 31, 2021. Those without nasal obstruction before surgery or with a short follow-up period (< 28 days) were excluded from the survey analysis.
Of the 20 patients (mean age, 48.0 [range, 19-65] years), 17 (85.0%) were male, and three (15.0%) were female. A significant change was noted in the mean nasal obstruction symptom evaluation score (68.2 vs. 15.0, P < .001) in the 17 patients included in the analysis. Postoperative endoscopic evaluation revealed a straight septum in 19/20 (95.0%) patients, and no complications were noted in the postoperative follow-up period of up to 364 days.
The three-dimensional printed polycaprolactone nasal mesh is safe and provides adequate support to resist the intrinsic memory of the cartilage of the caudal septum. In addition to nasal surgeries, it has great potential as a graft in other reconstructive surgeries. Trial registration Retrospectively registered.
三维打印聚己内酯网片在动物和人体模型中均已证明具有良好的生物相容性和稳定性，可用于鼻外科。然而，作为治疗鼻中隔后段偏曲的夹板移植材料的安全性和耐久性尚未得到证实。本研究旨在探讨三维打印聚己内酯网片夹板移植在鼻中隔成形术中的疗效和安全性，采用楔形切除术治疗鼻中隔后段偏曲。
本回顾性研究纳入了 2019 年 12 月 1 日至 2021 年 5 月 31 日期间在韩国一家三级医疗机构因鼻中隔后段偏曲接受鼻中隔成形术联合三维打印聚己内酯网片夹板移植的 20 例年龄≥18 岁患者的病历资料。排除术前无鼻塞或随访时间<28 天的患者。
20 例患者（平均年龄，48.0 [范围，19-65] 岁）中，17 例（85.0%）为男性，3 例（15.0%）为女性。在纳入分析的 17 例患者中，平均鼻塞症状评估评分有显著变化（68.2 比 15.0，P<0.001）。术后内镜评估显示 20 例（95.0%）患者鼻中隔呈直线状，术后随访 364 天内无并发症发生。
三维打印聚己内酯鼻网片安全且提供足够的支撑力，可抵抗鼻中隔后段软骨的固有记忆。除了鼻部手术，它在其他重建手术中也有很大的应用潜力。
回顾性注册。
