Koo Bon Min, Jeong Jong In
Department of Otolaryngology, Keimyung University School of Medicine, Dongsan Hospital, Daegu, Republic of Korea.
Int Arch Otorhinolaryngol. 2023 Oct 23;27(4):e699-e705. doi: 10.1055/s-0043-1761168. eCollection 2023 Oct.
Nasoseptal flap is widely used in reconstruction of the skull base to prevent cerebrospinal fluid leakage after surgery for skull base lesions. There has been a debate on whether more severe olfactory dysfunction occurs after nasoseptal flap elevation than the conventional trans-sphenoidal approach. To compare the long-term recovery patterns associated with nasoseptal flap and the conventional trans-sphenoidal approach. The subjects were divided into the conventional trans-sphenoidal approach group and the nasoseptal flap elevation group. We followed up self-reported olfactory score using the visual analogue scale and threshold discrimination identification (TDI) score of the Korean Version of the Sniffin Stick test II for 12 months, with olfactory training. The study included 31 patients who underwent the trans-sphenoidal approach. Compared with preoperative status, the mean visual analogue scale and TDI scores in the conventional trans-sphenoidal approach group recovered 2 months postoperatively, while in the nasoseptal flap elevation group the visual analogue scale and TDI scores recovered 6 months and 3 months after surgery, respectively. Twelve months after surgery, the visual analogue scale and TDI scores in the conventional trans-sphenoidal approach group were 9.3 ± 0.5 and 28.5 ± 4.3, while those from the nasoseptal flap elevation group were 8.9 ± 1.5 and 27.2 ± 4.7 ( = 0.326; 0.473). Only one of the patients in the nasoseptal flap elevation group had permanent olfactory dysfunction. The olfactory function recovered more gradually in the nasoseptal flap elevation group than in the conventional trans-sphenoidal approach group, but there was no difference between the two groups after 6 months.
鼻中隔瓣广泛应用于颅底重建,以预防颅底病变手术后的脑脊液漏。关于鼻中隔瓣掀起术后是否比传统经蝶窦入路会出现更严重的嗅觉功能障碍,一直存在争议。 为比较鼻中隔瓣与传统经蝶窦入路相关的长期恢复模式。 将受试者分为传统经蝶窦入路组和鼻中隔瓣掀起组。我们使用视觉模拟量表对自我报告的嗅觉评分进行随访,并采用韩国版嗅觉棒测试II的阈值辨别识别(TDI)评分,进行为期12个月的嗅觉训练。 该研究纳入了31例行经蝶窦入路手术的患者。与术前状态相比,传统经蝶窦入路组的平均视觉模拟量表和TDI评分在术后2个月恢复,而鼻中隔瓣掀起组的视觉模拟量表和TDI评分分别在术后6个月和3个月恢复。术后12个月,传统经蝶窦入路组的视觉模拟量表和TDI评分分别为9.3±0.5和28.5±4.3,而鼻中隔瓣掀起组的分别为8.9±1.5和27.2±4.7(P = 0.326;0.473)。鼻中隔瓣掀起组中只有1例患者存在永久性嗅觉功能障碍。 鼻中隔瓣掀起组的嗅觉功能恢复比传统经蝶窦入路组更缓慢,但6个月后两组之间无差异。
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