Santa Casa de Misericórdia de São Paulo, Departamento de Otorrinolaringologia, São Paulo, SP, Brazil; Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, SP, Brazil.
Santa Casa de Misericórdia de São Paulo, Departamento de Otorrinolaringologia, São Paulo, SP, Brazil; Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, SP, Brazil.
Braz J Otorhinolaryngol. 2022 Jan-Feb;88(1):15-21. doi: 10.1016/j.bjorl.2020.03.006. Epub 2020 Apr 27.
Endoscopic transnasal access to the skull base, both for treatment and reconstruction, can cause olfactory morbidity. Knowing the main consequences of this intervention is essential to have objective criteria for decision-making regarding the appropriate surgical technique.
The aim of this study is to determine the impact on olfactory function of the endonasal endoscopic access to the skull base with the creation of the nasoseptal flap.
A prospective research was carried out in which 22 patients who underwent endoscopic transnasal surgery at the skull base, with the creation of a nasoseptal flap. The Connecticut Chemosensory Clinical Research Center test was applied before and at the 1, 3 and 6 postoperative months.
The results showed that only in the first month of follow-up the mean patient classification was statistically worse than at the other evaluation moments (p<0.05), but there was no mean difference in the Connecticut score classification between the other moments (p>0.05); that is, patients showed worsening in the 1 month and returned to the preoperative mean after the 3 month of follow-up.
The present study showed that the postoperative decrease in olfaction is transient, since the patient's sense of smell returns to pre-surgical values in the 3 postoperative month.
经鼻内镜入路进行颅底治疗和重建可能会导致嗅觉障碍。了解这种干预的主要后果对于决策合适的手术技术至关重要。
本研究旨在确定经鼻内镜颅底入路并创建鼻中隔-鼻甲瓣对嗅觉功能的影响。
前瞻性研究，22 例患者在颅底行内镜经鼻手术，并创建鼻中隔-鼻甲瓣。术前和术后第 1、3、6 个月应用康涅狄格化学感觉临床研究中心测试。
结果显示，只有在随访的第一个月，患者的分类均值明显比其他评估时间差（p<0.05），但在其他时间点，康涅狄格评分分类之间没有均值差异（p>0.05）；也就是说，患者在第 1 个月嗅觉下降，在随访第 3 个月后恢复到术前平均水平。
本研究表明，术后嗅觉下降是短暂的，因为患者的嗅觉在术后第 3 个月恢复到术前水平。
