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羊水栓塞与新型冠状病毒肺炎:病例报告

Amniotic fluid pulmonary embolism and COVID-19: Case report.

作者信息

Masmela Garcia Karla Melissa, García Agudelo Lorena, Duran Mayorga Carlos Andrés, Gualteros Lara César David, Velasco Castro Julio César

机构信息

Regional Hospital of the Orinoquia, Yopal, Colombia.

出版信息

Radiol Case Rep. 2023 Oct 14;18(12):4507-4509. doi: 10.1016/j.radcr.2023.09.059. eCollection 2023 Dec.

DOI:10.1016/j.radcr.2023.09.059
PMID:37876891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10590762/
Abstract

Amniotic fluid embolism is a rare complication of peripartum. It is caused by the entry of fetal components into the maternal systemic circulation. There are 2 main types: typical; it presents with the triad of hemodynamic collapse, respiratory distress and disseminated intravascular coagulation type coagulopathy, while atypical; disseminated intravascular coagulation does not occur. SARS CoV-2 infection causes coagulopathy due to the alteration of Virchow's triad and coagulation factors. We present the case of a 21-year-old pregnant woman who consulted for premature rupture of membranes, with an indication for cesarean section, and during surgery presented bradycardia, hypotension, and desaturation until cardiorespiratory arrest. An angiotomography showed amniotic fluid embolism associated with pulmonary edema, ruling out differential diagnoses associated with the disease, leaving as the only cause of the infection confirmed by COVID-19, which, it was inferred, was closely related to the immunological disorder suffered by the patient.

摘要

羊水栓塞是围产期一种罕见的并发症。它是由胎儿成分进入母体体循环引起的。主要有两种类型:典型型,表现为血流动力学崩溃、呼吸窘迫和弥散性血管内凝血型凝血病三联征;非典型型,不发生弥散性血管内凝血。严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染由于维勒三联征和凝血因子的改变而导致凝血病。我们报告一例21岁孕妇的病例,该孕妇因胎膜早破就诊,有剖宫产指征,手术期间出现心动过缓、低血压和血氧饱和度下降,直至心肺骤停。血管造影显示羊水栓塞合并肺水肿,排除了与该疾病相关的鉴别诊断,确诊感染为2019冠状病毒病(COVID-19),据推断,这与患者所患的免疫紊乱密切相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36b4/10590762/5cece7f2e258/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36b4/10590762/5cece7f2e258/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36b4/10590762/5cece7f2e258/gr1.jpg

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本文引用的文献

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COVID-19 Infection Complicated by Disseminated Intravascular Coagulation during Pregnancy-Two Cases Report.COVID-19感染合并妊娠期弥散性血管内凝血——两例报告
Diagnostics (Basel). 2022 Mar 8;12(3):655. doi: 10.3390/diagnostics12030655.
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Disseminated intravascular coagulation type of amniotic fluid embolism: a challenging case report with favorable outcome.弥漫性血管内凝血型羊水栓塞:一例极具挑战性但结局良好的病例报告。
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Immune storm and coagulation storm in the pathogenesis of amniotic fluid embolism.免疫风暴和凝血风暴在羊水栓塞发病机制中的作用。
Eur Rev Med Pharmacol Sci. 2021 Feb;25(4):1796-1803. doi: 10.26355/eurrev_202102_25073.
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Haemostatic and thrombo-embolic complications in pregnant women with COVID-19: a systematic review and critical analysis.COVID-19 孕妇的止血和血栓栓塞并发症:系统评价和批判性分析。
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Early Diagnosis of the Cardiopulmonary Collapse Type of Amniotic Fluid Embolism with Obstetrical Disseminated Intravascular Coagulation during Elective Cesarean Section : A Case Report.择期剖宫产术中并发产科弥漫性血管内凝血致羊水栓塞性心肺功能衰竭的早期诊断:1 例报告。
J Med Invest. 2020;67(1.2):207-210. doi: 10.2152/jmi.67.207.
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Risk factors, management, and outcomes of amniotic fluid embolism: A multicountry, population-based cohort and nested case-control study.羊水栓塞的风险因素、管理和结局:一项多国、基于人群的队列研究和巢式病例对照研究。
PLoS Med. 2019 Nov 12;16(11):e1002962. doi: 10.1371/journal.pmed.1002962. eCollection 2019 Nov.
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Evaluation of proposed criteria for research reporting of amniotic fluid embolism.羊水栓塞研究报告拟议标准的评估
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Amniotic fluid embolism: antepartum, intrapartum and demographic factors.羊水栓塞:产前、产时及人口统计学因素
J Matern Fetal Neonatal Med. 2015 May;28(7):793-8. doi: 10.3109/14767058.2014.932766. Epub 2014 Jun 30.