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肝病中血管内凝血的研究:肝硬化中的可溶性纤维蛋白单体复合物

Investigations on intravascular coagulation in liver disease: souble fibrin monomer complexes in liver cirrhosis.

作者信息

Coccheri S, Palareti G, Dalmonte P R, Poggi M, Boggian O

出版信息

Haemostasis. 1979;8(1):8-18. doi: 10.1159/000214286.

DOI:10.1159/000214286
PMID:378778
Abstract

Souble fibrin monomer complexes (SFMC) have been quantitated in 18 patients with liver cirrhosis by means of plasma gel filtration on an agarose column. The concentration of SFMC (as related to total fibrinogen) was increased in cirrhotic patients. The difference between controls and patients, as well as the difference between compensated and decompensated cirrhotic subjects, was statisically significant. Although these data, together with the results of heparin administration in one reported case, suggest intravascular coagulation, some alternative explanations should also be considered.

摘要

通过琼脂糖柱上的血浆凝胶过滤法对18例肝硬化患者的可溶性纤维蛋白单体复合物(SFMC)进行了定量分析。肝硬化患者的SFMC浓度(相对于总纤维蛋白原)升高。对照组与患者之间以及代偿期与失代偿期肝硬化患者之间的差异具有统计学意义。尽管这些数据以及一篇报道病例中肝素给药的结果提示存在血管内凝血,但也应考虑一些其他解释。

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Investigations on intravascular coagulation in liver disease: souble fibrin monomer complexes in liver cirrhosis.肝病中血管内凝血的研究:肝硬化中的可溶性纤维蛋白单体复合物
Haemostasis. 1979;8(1):8-18. doi: 10.1159/000214286.
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