Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, 030032, China.
Shanxi Province Clinical Research Center for Dermatologic and Immunologic Diseases (Rheumatic Diseases), Taiyuan, China.
Inflamm Res. 2023 Dec;72(12):2089-2109. doi: 10.1007/s00011-023-01797-x. Epub 2023 Oct 25.
The pathogenesis, diagnosis, and treatment of Sjögren's syndrome (SS) face many challenges, and there is an urgent need to develop new technologies to improve our understanding of SS.
By searching the literature published domestically and internationally in the past 20 years, this artical reviewed the research of various omics techniques in SS.
Omics technology provided valuable insights into the pathogenesis, early diagnosis, condition and efficacy evaluation of SS. It is helpful to reveal the pathogenesis of the disease and explore new treatment schemes, which will open a new era for the study of SS.
At present, omics research has made some gratifying achievements, but there are still many uncertainties. Therefore, in the future, we should improve research techniques, standardize the collection of samples, and adopt a combination of multi-omics techniques to jointly study the pathogenesis of SS and provide new schemes for its treatment.
干燥综合征（SS）的发病机制、诊断和治疗面临诸多挑战，迫切需要开发新技术以提高我们对 SS 的认识。
通过检索国内外近 20 年来发表的文献，本文综述了各种组学技术在 SS 中的研究进展。
组学技术为 SS 的发病机制、早期诊断、病情和疗效评估提供了有价值的见解，有助于揭示疾病的发病机制并探索新的治疗方案，将为 SS 的研究开辟一个新时代。
目前，组学研究已经取得了一些可喜的成果，但仍存在许多不确定性。因此，未来应提高研究技术，规范样本采集，采用多种组学技术相结合的方法共同研究 SS 的发病机制，并为其治疗提供新的方案。
