Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Shock. 2024 Apr 1;61(4):509-519. doi: 10.1097/SHK.0000000000002242. Epub 2023 Sep 29.
Hemorrhagic shock (HS) is a common complication after traumatic injury. Early identification of HS can reduce patients' risk of death. Currently, the identification of HS relies on macrocirculation indicators such as systolic blood pressure and heart rate, which are easily affected by the body's compensatory functions. Recently, the independence of the body's overall macrocirculation from microcirculation has been demonstrated, and microcirculation indicators have been widely used in the evaluation of HS. In this study, we reviewed the progress of research in the literature on the use of microcirculation metrics to monitor shock. We analyzed the strengths and weaknesses of each metric and found that microcirculation monitoring could not only indicate changes in tissue perfusion before changes in macrocirculation occurred but also correct tissue perfusion and cell oxygenation after the macrocirculation index returned to normal following fluid resuscitation, which is conducive to the early prediction and prognosis of HS. However, microcirculation monitoring is greatly affected by individual differences and environmental factors. Therefore, the current limitations of microcirculation assessments mean that they should be incorporated as part of an overall assessment of HS patients. Future research should explore how to better combine microcirculation and macrocirculation monitoring for the early identification and prognosis of HS patients.
失血性休克(HS)是创伤后常见的并发症。早期识别 HS 可以降低患者的死亡风险。目前,HS 的识别依赖于收缩压和心率等宏观循环指标,这些指标很容易受到机体代偿功能的影响。最近,已经证明了机体整体宏观循环与微循环的独立性,并且微循环指标已广泛用于 HS 的评估。在本研究中,我们回顾了文献中关于使用微循环指标监测休克的研究进展。我们分析了每个指标的优缺点,发现微循环监测不仅可以在宏观循环发生变化之前指示组织灌注的变化,而且可以在液体复苏后宏观循环指数恢复正常时纠正组织灌注和细胞氧合,有利于 HS 的早期预测和预后。然而,微循环监测受到个体差异和环境因素的极大影响。因此,目前微循环评估的局限性意味着应将其纳入 HS 患者的整体评估的一部分。未来的研究应探讨如何更好地结合微循环和宏观循环监测,以早期识别和预测 HS 患者。