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用于前列腺癌患者分期和随访的海绵骨密度测定

Spongious bone density determination for staging and follow-up of patients with prostatic cancer.

作者信息

Golimbu M, Golimbu C, Firooznia H, Rafii M, Al-Askari S, Morales P

出版信息

Urology. 1986 Dec;28(6):534-9. doi: 10.1016/0090-4295(86)90163-9.

DOI:10.1016/0090-4295(86)90163-9
PMID:3787930
Abstract

Quantitative computerized tomography (QCT) of vertebral bodies could reveal metastatic spread of prostatic cancer before such lesions are seen with standard examinations. Focal increase in the density of the spongious bone in face of normal bone scan and serum acid phosphatase is suggestive of metastasis, but certitude is gained only if further increase in density or structural bone changes are demonstrated on follow-up studies. QCT also may provide an objective measurement of tumor response to therapy.

摘要

椎体的定量计算机断层扫描(QCT)能够在标准检查发现前列腺癌转移灶之前揭示其转移扩散情况。在骨扫描和血清酸性磷酸酶正常的情况下,海绵状骨密度局灶性增加提示转移,但只有在后续研究中证实密度进一步增加或出现骨质结构改变时才能确诊。QCT还可以对肿瘤治疗反应提供客观测量。

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