Aparato Digestivo, Hospital Universitario Clínico San Cecilio, España.
Aparato Digestivo, Hospital Clínico Universitario San Cecilio, España.
Rev Esp Enferm Dig. 2024 Aug;116(8):459-460. doi: 10.17235/reed.2023.9989/2023.
Doxycycline is a bacteriostatic antibiotic of the tetracycline group widely indicated in the treatment of numerous infections (skin, soft tissues...). Given its acid nature, doxycycline is able to potentially generate mucous damage acting as a caustic; therefore, when the capsule of doxycycline (high concentrated substance) is taken inappropriately (with a small quantity of liquid or just before laying down) and remains for a longer time in contact with the esophagus, doxycycline may cause esophagitis-type lesions and ulcerations.
多西环素是一种属于四环素类的抑菌抗生素,广泛用于治疗多种感染(皮肤、软组织等)。由于其酸性性质,多西环素有潜在的黏膜损伤作用,具有腐蚀性;因此,当多西环素胶囊(高浓度物质)被不当服用(液体量少或刚躺下时服用)且在食管中停留时间较长时,多西环素可能会引起食管炎样病变和溃疡。