Taguchi K, Reding R, Urbaszek W, Klinkmann H
Z Exp Chir Transplant Kunstliche Organe. 1986;19(5):270-8.
Based on implantation experiments in calves resulted some experiences for the implantation technic of artificial hearts. After resection of the natural ventricles and of the valvular parts of the aorta and pulmonary artery the connectors should be adapted and implanted. The first connected left ventricle get a caudal-lateral traction especially under supervision of the pulmonary veins and optimal development of the aorta. During connection of the right ventricle it is necessary to check up the inflow - and outflow tract situation. May be, the left ventricle get with this maneuver an unfavourable caudal kinking. Careful preparation and splitting of the pericardium is necessary to avoid obstructions for the venous flow. The closing of the chest and initial changes in position of the animal may alternate good positions of the heart, if the resection as well as preparation, adaptation and bedding don't remarked the discussed principles. One of the most relevant aspects in achieving the consistent survival of an animal undergoing the experimental implantation of a total artificial heart is obviously related to the correct anatomic placement of prosthetic ventricles inside the chest. In this case, the skillful surgical procedures based on an established surgical principle are considered to be attributable in obtaining the optimal hemodynamic situation. Description of the surgical procedures has been made elsewhere. However, it has been difficult to find a well defined surgical principle although particular milestone has already been made by a clinical application of the total artificial heart in 1982. Although the presently available prosthetic ventricles generally fit better in the chest, the problems in design and size of the prosthesis still exist.(ABSTRACT TRUNCATED AT 250 WORDS)
基于在小牛身上的植入实验，获得了一些关于人工心脏植入技术的经验。在切除天然心室以及主动脉和肺动脉的瓣膜部分后，应适配并植入连接器。首先连接的左心室应向尾外侧牵引，尤其是在肺静脉的监测下以及主动脉实现最佳发育的情况下。在连接右心室时，有必要检查流入道和流出道的情况。可能通过此操作，左心室会出现不利的尾侧扭结。小心地准备和切开心包对于避免静脉血流受阻是必要的。如果切除以及准备、适配和安置过程未遵循所讨论的原则，关闭胸腔以及动物初始体位的改变可能会改变心脏的良好位置。在使接受全人工心脏实验植入的动物持续存活方面，最相关的因素之一显然与人工心室在胸腔内的正确解剖位置有关。在这种情况下，基于既定手术原则的熟练手术操作被认为有助于获得最佳的血流动力学状况。手术操作的描述已在其他地方给出。然而，尽管1982年全人工心脏的临床应用已经取得了特定的里程碑，但一直难以找到一个明确界定的手术原则。尽管目前可用的人工心室通常在胸腔内适配得更好，但假体在设计和尺寸方面的问题仍然存在。（摘要截取自250词）
