Montanari M, Violi V, Roncoroni L, De Bernardinis M, Mora G, Ronzoni M, Peracchia A
Acta Chir Scand. 1986 Aug-Sep;152:527-30.
In 15 patients about to undergo colorectal resection for cancer (group I), body weight, lymphocytes, albumin, prealbumin, complement components C3 and C4 and total hemolytic complement activity (TC) were evaluated on admission to hospital and after preroperative preparation which involved dietary restrictions for 5-9 days (450 calories, 25 g protein daily). The same parameters were evaluated in 15 patients admitted for other major surgery not requiring colonic preparation (group II). Statistically significant reduction in prealbumin, C3, C4 and TC were found only in group I. The observations suggest a relationship between immunonutritional status and preparation for large-bowel surgery, reproducing a state of acute malnutrition.
对15例即将接受结直肠癌切除术的患者（第一组），在入院时以及术前准备（包括5 - 9天的饮食限制，每天450卡路里、25克蛋白质）后，评估其体重、淋巴细胞、白蛋白、前白蛋白、补体成分C3和C4以及总溶血补体活性（TC）。对15例因其他大手术入院且无需结肠准备的患者（第二组）评估相同参数。仅在第一组中发现前白蛋白、C3、C4和TC有统计学意义的降低。这些观察结果表明免疫营养状态与大肠手术准备之间存在关联，重现了急性营养不良状态。
