Deepika Burra Anand, Ramamurthy Jaiganesh
Department of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Bioinformation. 2023 May 31;19(5):590-594. doi: 10.6026/97320630019590. eCollection 2023.
(Tulsi) has various properties like antibacterial, anti-inflammatory and anti-oxidant. To compare the effect of the local-drug delivery system containing 2% (Tulsi) as an adjunct to scaling and root planing (SRP).The main aim of the study was to evaluate the efficacy of (Tulsi) gel with Tetracycline fibers (Actisite) for the treatment of periodontitis patients. 40 subjects with periodontitis (pocket depth of 5 mm) were selected and divided into 2 groups Group I: (Tulsi) gel (n= 20) and Group II: Tetracycline fibers (Actisite) (n = 20). Clinical parameters assessed were Gingival Index , Plaque Index , Probing Depth and Clinical Attachment Loss were assessed at baseline, 1 month, 3 months, 6 months, 8 months. Our results showed that Gingival index and Plaque index for for GROUP I: (Tulsi) and GROUP II: Tetracycline fibers (Actisite)are not statistically significant p>0.05 for baseline, at 1 month, 3 months, 6 months, 8 months. Probing depth and Clinical attachment are not significant p>0.05 for baseline, at 1 month, 3 months, 6 months, and statistically significant difference seen at 8 months p<0.05. 2% (Tulsi) gel can be effectively used as an adjunct to scaling and root planing. When used as an adjunct to scaling and root planing, it helps in reduction of pocket depth and gain of clinical attachment. (Tulsi) showed promising results when compared to Tetracycline fibers (Actisite).
（罗勒）具有抗菌、抗炎和抗氧化等多种特性。为比较含2%（罗勒）的局部给药系统作为龈下刮治和根面平整（SRP）辅助治疗的效果。本研究的主要目的是评估（罗勒）凝胶与四环素纤维（Actisite）治疗牙周炎患者的疗效。选取40例牙周炎患者（牙周袋深度为5mm），分为2组。第一组：（罗勒）凝胶组（n = 20），第二组：四环素纤维（Actisite）组（n = 20）。评估的临床参数包括牙龈指数、菌斑指数、探诊深度和临床附着丧失，在基线、1个月、3个月、6个月、8个月时进行评估。我们的结果显示，第一组：（罗勒）凝胶组和第二组：四环素纤维（Actisite）组的牙龈指数和菌斑指数在基线、1个月、3个月、6个月、8个月时无统计学意义（p>0.05）。探诊深度和临床附着在基线、1个月、3个月、6个月时无显著差异（p>0.05），在8个月时存在统计学显著差异（p<0.05）。2%（罗勒）凝胶可有效用作龈下刮治和根面平整的辅助治疗。当用作龈下刮治和根面平整的辅助治疗时，有助于减少牙周袋深度并增加临床附着。与四环素纤维（Actisite）相比，（罗勒）显示出有前景的结果。
