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使用来自罗勒(图尔西)的凝胶和洗必泰(CHX)治疗牙龈炎的比较临床数据。

Comparative clinical data for gingivitis treatment using gels from (Tulsi) and chlorhexidine (CHX).

作者信息

Deepika B A, Ramamurthy Jaiganesh, Jayakumar Nadathur Duraisamy, Rajesh Kumar S

机构信息

Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamilnadu, India.

出版信息

Bioinformation. 2021 Dec 31;17(12):1091-1098. doi: 10.6026/973206300171091. eCollection 2021.

Abstract

(Tulsi) has various properties like anti bacterial, anti inflammatory, anti oxidant for curing diseases. It is a plant with known medicinal value in Indian system of medicine. Therefore, it is of interest to evaluate the effectiveness of with Chlorhexidine (CHX) which is a standard material for the treatment of gingivitis. We used 30 gingivitis subjects divided into 2 groups. Group I used Tulsi gel (n= 15) and Group II used CHX gel (n = 15) for treatment. Tulsi and CHX gel use was advised for 1 month. The Clinical parameters assessed were gingival Index (GI), plaque Index (PI), probing depth (PD) and clinical attachment loss (CAL) assessed at a time interval of 30 days. Statistical analysis was completed using the SPSS software 23.0. Data showed that GI and PD for Tulsi and CHX in pre and post groups are not significant with p > 0.05. Moreover, PI is not significant with p>0.05 among pre Tulsi, pre CHX and post CHX. However, data is significant with p<0.05 for Tulsi group. CAL is significant with p<0.05 among pre/post Tulsi groups. However, this is not significant with p>0.05 among pre/post CHX groups. Data shows that 2% of Tulsi is effective in reducing gingival bleeding and inflammation. Thus, clinical data shows that Tulsi gel is promising for the treatment of gingivitis.

摘要

(图尔西)具有抗菌、抗炎、抗氧化等多种特性,可用于治疗疾病。它是印度医学体系中一种具有已知药用价值的植物。因此,评估其与洗必泰(CHX)(一种治疗牙龈炎的标准药物)相比的有效性很有意义。我们将30名牙龈炎患者分为两组。第一组使用图尔西凝胶(n = 15),第二组使用CHX凝胶(n = 15)进行治疗。建议使用图尔西凝胶和CHX凝胶1个月。评估的临床参数包括牙龈指数(GI)、菌斑指数(PI)、探诊深度(PD)和临床附着丧失(CAL),每隔30天进行一次评估。使用SPSS软件23.0完成统计分析。数据显示,图尔西组和CHX组治疗前后的GI和PD差异不显著,p>0.05。此外,图尔西组治疗前、CHX组治疗前和CHX组治疗后的PI差异不显著,p>0.05。然而,图尔西组的数据差异显著,p<0.05。图尔西组治疗前后的CAL差异显著,p<0.05。然而,CHX组治疗前后的CAL差异不显著,p>0.05。数据表明,2%的图尔西在减少牙龈出血和炎症方面有效。因此,临床数据表明图尔西凝胶在治疗牙龈炎方面具有前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99b9/8900163/f757d56f46d0/973206300171091F1.jpg

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