Auer L M, Oberbauer R W, Clarici G, Pucher R
Acta Neurochir (Wien). 1986;82(3-4):102-9. doi: 10.1007/BF01456368.
This prospective open study of 124 patients [80% with completed stroke (CS), 16% with TIAS, 4% with PRIND] consecutively admitted between 1976 and 1981 investigates the rates of reinfarction after surgical treatment (extra-intracranial arterial bypass, EIAB and/or carotid thrombendarterectomy, TEA). 34% of patients had unilateral carotid stenosis, 26% unilateral internal carotid artery occlusion, 17% had occlusion of one and stenosis of the contralateral internal carotid artery, 14% bilateral carotid stenosis. Combined surgical morbidity and mortality was 5% after 158 operations in 124 patients; 7 of the 8 complications occurred in patients with CS. Of the 120 survivors in the immediate postoperative period, after a mean follow-up period of 5.7 years ranging from 3-8 years, an infarct occurred in 5.8%, i.e., 1% per year; 3 of them occurred ipsilaterally, 2 contralaterally to the first infarct, two remained unknown. Among all 99 patients with CS, the reinfarction rate was 5% (1% per year); in CS patients with a minimal follow-up of 5 years, the annual reinfarction rate was 2%. Of fifty-three patients with completed stroke after EIAB with a mean follow-up of 4.6 years, 3.8% suffered reinfarction (0.8% per year). Among 26 patients with CS and unilateral carotid occlusion after a mean follow-up of 4.7 years, the reinfarction rate was 3.9% (0.8% per year). Among 46 patients with carotid occlusion with or without further stenotic or occlusive lesions, the reinfarction rate was 2.2%.(ABSTRACT TRUNCATED AT 250 WORDS)
这项前瞻性开放性研究纳入了1976年至1981年间连续收治的124例患者[80%为完全性卒中(CS),16%为短暂性脑缺血发作(TIAS),4%为可逆性缺血性神经功能缺损(PRIND)],调查了手术治疗(颅外-颅内动脉搭桥术,EIAB和/或颈动脉内膜切除术,TEA)后的再梗死率。34%的患者有单侧颈动脉狭窄,26%有单侧颈内动脉闭塞,17%有一侧闭塞且对侧颈内动脉狭窄,14%有双侧颈动脉狭窄。124例患者接受了158次手术,手术合并发病率和死亡率为5%;8例并发症中有7例发生在CS患者中。术后即刻有120例幸存者,平均随访期为5.7年(3 - 8年),5.8%的患者发生了梗死,即每年1%;其中3例发生在同侧,2例发生在首次梗死的对侧,2例情况不明。在所有99例CS患者中,再梗死率为5%(每年1%);在随访至少5年的CS患者中,年再梗死率为2%。在平均随访4.6年的EIAB术后完全性卒中的53例患者中,3.8%发生了再梗死(每年0.8%)。在平均随访4.7年的26例CS合并单侧颈动脉闭塞的患者中,再梗死率为3.9%(每年0.8%)。在46例有或无进一步狭窄或闭塞性病变的颈动脉闭塞患者中,再梗死率为2.2%。(摘要截选至250字)