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是否应该免费或补贴提供 HIV 疫苗?坦桑尼亚 HIV 疫苗试验利益相关者的定性研究。

Should HIV Vaccines Be Made Available at No or Subsidized Cost? A Qualitative Inquiry of HIV Vaccine Trial Stakeholders in Tanzania.

机构信息

Department of Bioethics and Health Professionalism, School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.

Department of Behavioral Sciences, School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.

出版信息

AJOB Empir Bioeth. 2024 Jul-Sep;15(3):206-213. doi: 10.1080/23294515.2023.2274599. Epub 2023 Oct 27.

Abstract

BACKGROUND

The world has come closer than ever to discovering a viable HIV vaccine. However, it remains less certain whether HIV vaccines should be made available to participants and communities in which trials are run no or subsidized cost. Hence the essence of this inquiry.

METHODOLOGY

This is a case study design using in-depth interviews (IDI) and focus group discussions (FGD) with researchers of HIV vaccine trials, institutional review board (IRB) members, HIV advocates, a policy maker, and members of community advisory board (CAB) in Tanzania. Participants were purposively selected and data thematically analyzed using MAXQDA software.

RESULTS

Hosting a vaccine trial and the financial incapacity of individuals at increased risk of HIV were among the reasons in favor of free access to HIV vaccines. In contrast, the view that vaccines should be provided at a subsidized cost was related to high costs of vaccine development, financial return expectations by investors, and the fear of labeling the free vaccine as less important. Moreover, apart from governments and international organizations, well-off individuals could share the cost burden.

CONCLUSION

Stakeholders engaging in active discussion about sharing the viable vaccine ought to take the aforementioned concerns into account and ensure unhindered access to individuals and host communities in Tanzania and beyond.

摘要

背景

世界比以往任何时候都更接近发现一种可行的 HIV 疫苗。然而,HIV 疫苗是否应该以免费或补贴的价格提供给试验所在的参与者和社区,这一点仍然不太确定。因此,有了本次调查。

方法

这是一项案例研究设计,采用深度访谈(IDI)和焦点小组讨论(FGD)的方法,对 HIV 疫苗试验的研究人员、机构审查委员会(IRB)成员、HIV 倡导者、政策制定者和坦桑尼亚社区咨询委员会(CAB)成员进行了研究。参与者是经过精心挑选的,使用 MAXQDA 软件对数据进行主题分析。

结果

主办疫苗试验和处于 HIV 高风险人群的个人的经济能力不足是支持免费获得 HIV 疫苗的原因之一。相比之下,认为疫苗应该以补贴价格提供的观点与疫苗开发的高成本、投资者的财务回报预期以及担心将免费疫苗贴上不重要的标签有关。此外,除了政府和国际组织外,富裕的个人也可以分担成本负担。

结论

参与有关共享可行疫苗的积极讨论的利益相关者应该考虑到上述问题,并确保坦桑尼亚及其他地区的个人和宿主社区能够不受阻碍地获得疫苗。

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本文引用的文献

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Can HIV vaccines be shared fairly? Perspectives from Tanzania.
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Global Health. 2022 Mar 5;18(1):26. doi: 10.1186/s12992-022-00801-z.
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