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[对比增强乳腺X线摄影术在乳腺癌诊断中的应用]

[Use of contrast-enhanced mammography for diagnosis of breast cancer].

作者信息

Fischer Uwe, Diekmann Felix, Helbich Thomas, Preibsch Heike, Püsken Michael, Wenkel Evelyn, Wienbeck Susanne, Fallenberg Eva Maria

机构信息

Diagnostisches Brustzentrum Göttingen, Göttingen, Deutschland.

Institut für Radiologische Diagnostik, Krankenhaus St. Joseph-Stift, Schwachhauser Heerstr. 54, 28209, Bremen, Deutschland.

出版信息

Radiologie (Heidelb). 2023 Dec;63(12):916-924. doi: 10.1007/s00117-023-01222-8. Epub 2023 Oct 27.

Abstract

BACKGROUND

Contrast-enhanced mammography (CEM) is an imaging method that is able to improve visualization of intramammary tumors after peripheral venous administration of an iodine-containing contrast medium (ICM).

OBJECTIVES AND METHODS

The current significance of CEM is discussed.

RESULTS

Studies were able to show an advantage of CEM in the diagnosis of breast cancer compared to mammography, especially for women with dense breasts. Indications for CEM currently depend on the availability of magnetic resonance imaging (MRI). If MRI is available, CEM is indicated in those cases when MRI cannot be performed. Use of CEM for breast cancer screening is currently viewed critically. This view can change when results and updated assessments of large CEM studies in Europe and USA become available. Patients must be informed about the use of an ICM. As ICM administration for CEM is carried out in a similar manner to established imaging methods, the authors expect the use of ICM for CEM to be unproblematic as long as general contraindications are adhered to.

CONCLUSIONS

In the future, CEM could have greater importance for the diagnosis of breast cancer, as this imaging method has diagnostic advantages compared to conventional mammography. A great advantage of CEM is its availability. For those who use breast MRI, CEM is helpful when MRI is not feasible due to contraindications or other reasons.

摘要

背景

对比增强乳腺X线摄影(CEM)是一种成像方法,能够在经外周静脉注射含碘造影剂(ICM)后改善乳腺内肿瘤的可视化。

目的与方法

讨论CEM的当前意义。

结果

研究表明,与乳腺X线摄影相比,CEM在乳腺癌诊断中具有优势,尤其是对于乳腺致密的女性。CEM的适应症目前取决于磁共振成像(MRI)的可用性。如果有MRI,在无法进行MRI的情况下则使用CEM。目前对CEM用于乳腺癌筛查持谨慎态度。当欧洲和美国大型CEM研究的结果和更新评估结果出来后,这种观点可能会改变。必须告知患者关于ICM的使用情况。由于CEM的ICM给药方式与既定的成像方法类似,作者预计只要遵守一般禁忌症,CEM使用ICM就不会有问题。

结论

未来,CEM对乳腺癌的诊断可能具有更重要的意义,因为这种成像方法与传统乳腺X线摄影相比具有诊断优势。CEM 的一个很大优势是其可用性。对于使用乳腺MRI的人来说,当由于禁忌症或其他原因无法进行MRI时,CEM会有所帮助。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10a2/10692004/ed11a69bdf06/117_2023_1222_Fig1_HTML.jpg

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