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65980 名欧洲老年人日常体力活动困难和握力与癌症诊断的关联。

Association of difficulties in daily physical activities and handgrip strength with cancer diagnoses in 65,980 European older adults.

机构信息

Exercise Intervention for Health Research Group (EXINH-RG), Department of Physiotherapy, University of Valencia, Valencia, Spain.

National Research Centre for the Working Environment, Copenhagen, Denmark.

出版信息

Aging Clin Exp Res. 2023 Dec;35(12):2971-2978. doi: 10.1007/s40520-023-02577-7. Epub 2023 Oct 27.

Abstract

BACKGROUND

People with cancer usually report physical deconditioning, which can limit daily activities.

AIMS

Our aim was to analyze associations between daily physical activities and handgrip strength with cancer diagnoses among European older adults.

METHODS

We used data from SHARE (a representative survey of individuals aged 50 years or older) wave 7, residing in 27 European countries and Israel. Participants self-reported difficulties in daily physical activities and cancer diagnoses, and handgrip strength was objectively assessed using a handheld dynamometer. Data were analyzed using binary logistic regression.

RESULTS

Overall, 65,980 participants (average age 67.6 years (SD = 9.4)) were analyzed. Having difficulties in any daily physical activity was significantly associated with higher odds of cancer diagnoses. Lower handgrip strength was significantly associated with cancer diagnoses among participants included in the first (adjusted odds ratio (AOR) = 1.27 [95%CI = 1.11-1.45]) and the second third (AOR = 1.15 [95%CI = 1.03-1.28]) when compared with participants from the last third in the final adjusted model.

DISCUSSION

Having difficulties in daily physical activities as well as lower levels of handgrip strength is positively associated with cancer diagnoses.

CONCLUSION

Adults with difficulties lifting or carrying weights over 5 kilos or having difficulties in two or more activities showed critical associations with cancer diagnosis.

摘要

背景

癌症患者通常会出现身体机能下降,从而限制日常活动。

目的

我们旨在分析欧洲老年人日常身体活动和握力与癌症诊断之间的关联。

方法

我们使用 SHARE(一项针对 50 岁及以上人群的代表性调查)第 7 波的数据,这些数据来自 27 个欧洲国家和以色列。参与者自我报告日常身体活动困难和癌症诊断情况,使用手持测力计客观评估握力。使用二项逻辑回归分析数据。

结果

共有 65980 名参与者(平均年龄 67.6 岁(SD=9.4))纳入分析。任何日常身体活动困难与癌症诊断的几率显著增加相关。与最后三分之一参与者相比,第一(调整后的优势比(AOR)=1.27[95%CI=1.11-1.45])和第二三分位(AOR=1.15[95%CI=1.03-1.28])的参与者中握力较低与癌症诊断显著相关。

讨论

日常身体活动困难以及握力水平较低与癌症诊断呈正相关。

结论

举起重物或搬运重物超过 5 公斤有困难或有两种或两种以上活动困难的成年人与癌症诊断有显著关联。

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