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石棉暴露与肾癌发生率的关联:证据权重评估与荟萃分析。

Association between Asbestos Exposure and the Incidence of Kidney Cancer: a Weight-of-Evidence Evaluation and Meta-analysis.

机构信息

Department of Health Policy and Management, Harvard TH Chan School of Public Health, Boston, MA, USA.

Department of Internal Medicine, Englewood Hospital and Medical Center, Englewood, NJ, USA.

出版信息

Curr Environ Health Rep. 2023 Dec;10(4):394-409. doi: 10.1007/s40572-023-00415-6.

Abstract

PURPOSE OF REVIEW

Occupational asbestos exposure has been extensively linked to various cancers, with ongoing debates regarding its association with kidney cancer. This study aims to investigate the correlation between occupational asbestos exposure and kidney cancer incidence. Additionally, potential influencing factors are analyzed to enhance the comprehension of the relationship between asbestos exposure and kidney cancer.

RECENT FINDING

While asbestos has established strong associations with malignant mesothelioma and lung cancer, its connection to other malignancies such as gastric, colorectal, and kidney cancers remains under scrutiny. The current study presents mixed opinions on the relationship between asbestos exposure and kidney cancer. Our analysis revealed a potential association between asbestos exposure and the incidence of kidney cancer. Notably, among different types of asbestos, exposure to amphibole appeared to be particularly linked to a higher incident risk of kidney cancer.

摘要

目的综述

职业性石棉暴露与各种癌症广泛相关,其与肾癌的关联仍存在争议。本研究旨在探讨职业性石棉暴露与肾癌发病率之间的相关性,并分析潜在的影响因素,以加深对石棉暴露与肾癌关系的理解。

最近发现

虽然石棉与恶性间皮瘤和肺癌有很强的关联,但它与胃癌、结直肠癌和肾癌等其他恶性肿瘤的关联仍在研究中。目前的研究对石棉暴露与肾癌之间的关系持不同意见。我们的分析显示,石棉暴露与肾癌的发病率之间存在潜在的关联。值得注意的是,在不同类型的石棉中,暴露于角闪石与肾癌发病风险的升高尤其相关。

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