Department of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, 11937 US Hwy 271, BMR Building, Tyler, TX 75708, USA.
Clin Chest Med. 2023 Dec;44(4):661-674. doi: 10.1016/j.ccm.2023.07.001. Epub 2023 Aug 23.
The field of environmental nontuberculous mycobacteria (NTM) is benefiting from a new era of genomics that has catapulted our understanding of preferred niches, transmission, and outbreak investigations. The ability to forecast environmental features that promote or reduce environmental NTM prevalence will greatly improve with coordinated environmental sampling and by elevating the necessity for uniform disease notifications. Studies that synergize environmental biology, isolate notifications, and comparative genomics in prospective, longitudinal studies, particularly during climate changes and weather events, will be useful to solve longstanding NTM public health quandaries.
环境非结核分枝杆菌（NTM）领域正受益于基因组学的新时代，这极大地推动了我们对其偏好生境、传播和暴发调查的理解。通过协调环境采样和提高对统一疾病通知的必要性，我们将能够更好地预测促进或减少环境 NTM 流行的环境特征。在气候变化和天气事件期间，将环境生物学、分离通知和比较基因组学协同应用于前瞻性、纵向研究的研究将有助于解决长期存在的 NTM 公共卫生难题。
