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食物来源的细胞外囊泡作为多生物活性复合物及其多样的健康效应

Food-Derived Extracellular Vesicles as Multi-Bioactive Complex and Their Versatile Health Effects.

作者信息

Yeo JuDong

机构信息

Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, Republic of Korea.

出版信息

Antioxidants (Basel). 2023 Oct 13;12(10):1862. doi: 10.3390/antiox12101862.

DOI:10.3390/antiox12101862
PMID:37891941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10604675/
Abstract

Extracellular vesicles (EVs) are membrane-bound organelles that are generally released by eukaryotic cells and enclose various cellular metabolic information, such as RNA, meta-proteins, and versatile metabolites. The physiological properties and diverse functions of food-derived EVs have been extensively elucidated, along with a recent explosive upsurge in EV research. Therefore, a concise review of the health effects of food-derived EVs is necessary. This review summarizes the structural stability and uptake pathways of food-derived EVs to target cells and their health benefits, including antioxidant, anti-inflammatory, and anticarcinogenic effects, gut microbiome modulation, and intestinal barrier enhancement.

摘要

细胞外囊泡（EVs）是膜结合细胞器，通常由真核细胞释放，并包裹各种细胞代谢信息，如RNA、元蛋白质和多种代谢产物。随着近年来EV研究的迅速兴起，食物来源的EVs的生理特性和多样功能已得到广泛阐明。因此，有必要对食物来源的EVs的健康影响进行简要综述。本综述总结了食物来源的EVs对靶细胞的结构稳定性、摄取途径及其健康益处，包括抗氧化、抗炎和抗癌作用、肠道微生物群调节以及肠道屏障增强。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b98/10604675/d5a3565009d7/antioxidants-12-01862-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b98/10604675/1ac115cf3361/antioxidants-12-01862-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b98/10604675/1dd896c5f6a2/antioxidants-12-01862-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b98/10604675/d5a3565009d7/antioxidants-12-01862-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b98/10604675/1ac115cf3361/antioxidants-12-01862-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b98/10604675/1dd896c5f6a2/antioxidants-12-01862-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b98/10604675/d5a3565009d7/antioxidants-12-01862-g003.jpg

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