Jianu Narcisa, Buda Valentina Oana, Căpățână Denisa, Muntean Călin, Onea Teodor Nicolae, Jivulescu Maria Anastasia, Teodor Ana, Romanescu Mirabela, Udrescu Lucreția, Groza Vlad, Udrescu Mihai, Buzatu Alina Ramona, Dehelean Cristina Adriana, Andor Minodora
Faculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, Timișoara, Romania.
Research Center for Pharmaco-Toxicological Evaluation, "Victor Babeș" University of Medicine and Pharmacy, Timișoara, Romania.
Front Med (Lausanne). 2024 Oct 23;11:1485382. doi: 10.3389/fmed.2024.1485382. eCollection 2024.
We aimed to investigate the knowledge and awareness level of osteoporosis, its risk factors, the possible causes of underdiagnosis, as well as the preventive measures and lifestyle behavior of the Romanian population.
A non-interventional, cross-sectional study was performed, consisting of an in-person survey, in 10 pharmacies located in both urban and rural settings in Romania. The survey was distributed to patients ≥40 years old.
Of 189 respondents, 78.8% were women, the majority age group being 60-69 (31.7%) and 50-59 (30.7%) years old and coming from urban areas (69.3%). Although 75.1% of participants declared knowing about osteoporosis, having a moderate level of knowledge, and women being more aware of the pathology, 77.3% have never performed a DXA test. Moreover, participants already diagnosed with osteoporosis did not show a better disease knowledge than those without a diagnosis. Nearly half of the respondents did not know that a family history of the disease increases the risk of developing it and 60% of them thought that symptoms may develop before a fracture occurs. The preventive strategies tend to be disregarded and thus, underused. Moreover, 42.9% of participants reported being diagnosed with osteoporosis, do not undergo treatment, although they are aware of the existence of effective strategies. The dataset was used to build a participant compatibility network. The network's clustering revealed six relevant communities, which are not correlated with questionnaire results but reflect the patterns of feature associations.
Preventive and therapeutic osteoporosis education programs are urgently needed in the Romanian population to decrease disability and high mortality risks and thus, to improve the quality of life.
我们旨在调查罗马尼亚人群对骨质疏松症及其危险因素的认知水平、诊断不足的可能原因以及预防措施和生活方式行为。
进行了一项非干预性横断面研究，包括在罗马尼亚城乡的10家药店进行的面对面调查。该调查面向40岁及以上的患者。
在189名受访者中，78.8%为女性，主要年龄组为60 - 69岁（31.7%）和50 - 59岁（30.7%），且来自城市地区（69.3%）。尽管75.1%的参与者表示了解骨质疏松症，知识水平中等，且女性对该疾病的认知度更高，但77.3%的人从未进行过双能X线吸收测定（DXA）检查。此外，已被诊断为骨质疏松症的参与者在疾病知识方面并不比未被诊断者表现更好。近一半的受访者不知道该疾病的家族史会增加患病风险，60%的人认为症状可能在骨折发生之前就出现。预防策略往往被忽视，因此未得到充分利用。此外，42.9%报告被诊断为骨质疏松症的参与者，尽管知道有有效的治疗策略，但并未接受治疗。该数据集用于构建参与者兼容性网络。网络聚类揭示了六个相关社区，它们与问卷结果无关，但反映了特征关联模式。
罗马尼亚人群迫切需要开展骨质疏松症的预防和治疗教育项目，以降低残疾和高死亡风险，从而提高生活质量。
