Confalonieri Filippo, Barone Gianmaria, Ferraro Vanessa, Ambrosini Giacomo, Gaeta Alessandro, Petrovski Beáta Éva, Lumi Xhevat, Petrovski Goran, Di Maria Alessandra
Department of Ophthalmology, IRCCS Humanitas Research Hospital, 20089 Milan, Italy.
Department of Biomedical Sciences, Humanitas University, 20090 Milan, Italy.
J Clin Med. 2023 Oct 20;12(20):6652. doi: 10.3390/jcm12206652.
: Vitreous hemorrhage (VH) is a common vitreoretinal condition causing impairment of vision due to various etiologies. No consensus exists on the best timing for performing pars plana vitrectomy (PPV) in fundus-obscuring VH. : Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards, we conducted a systematic review of the timing of PPV in VH. We assessed the strength of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach for all the included publications, in accordance with the 2011 Oxford Centre for Evidence-Based Medicine (OCEBM) recommendations. : A total of 1731 articles were identified. Following the removal of duplicates and screening of abstracts, 1203 articles remained. Subsequently, a comprehensive full-text review of 30 articles was conducted. Ultimately, 18 articles met the predefined inclusion criteria. : Despite the small number of studies on the timing of treatment for VH, the advantage of early over late PPV seems to be a reasonable approach in selected cases, and it might be considered modern standard care.
玻璃体积血（VH）是一种常见的玻璃体视网膜疾病，由于多种病因导致视力受损。对于眼底模糊的玻璃体积血患者，行玻璃体切割术（PPV）的最佳时机尚无共识。：按照系统评价和Meta分析的首选报告项目（PRISMA）标准，我们对玻璃体积血中行PPV的时机进行了系统评价。我们根据2011年牛津循证医学中心（OCEBM）的建议，采用推荐分级的评估、制定和评价（GRADE）方法对所有纳入的出版物评估证据强度。：共检索到1731篇文章。去除重复文献并筛选摘要后，剩余1203篇文章。随后，对30篇文章进行了全面的全文综述。最终，18篇文章符合预先设定的纳入标准。：尽管关于玻璃体积血治疗时机的研究数量较少，但在某些特定病例中，早期PPV优于晚期PPV似乎是一种合理的方法，并且可被视为现代标准治疗。
