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血液流变学和湍流模型在动脉瘤数值模拟中的影响

Influence of Blood Rheology and Turbulence Models in the Numerical Simulation of Aneurysms.

作者信息

Brambila-Solórzano Alberto, Méndez-Lavielle Federico, Naude Jorge Luis, Martínez-Sánchez Gregorio Josué, García-Rebolledo Azael, Hernández Benjamín, Escobar-Del Pozo Carlos

机构信息

Thermofluids Department, Faculty of Engineering, UNAM, Coyoacan, Mexico City C.P. 04510, Mexico.

Faculty of Mechanical and Electrical Engineering, Carretera Km 9 Colima-Coquimatlan, Colima C.P. 28400, Mexico.

出版信息

Bioengineering (Basel). 2023 Oct 8;10(10):1170. doi: 10.3390/bioengineering10101170.

DOI:10.3390/bioengineering10101170
PMID:37892900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10604493/
Abstract

An aneurysm is a vascular malformation that can be classified according to its location (cerebral, aortic) or shape (saccular, fusiform, and mycotic). Recently, the study of blood flow interaction with aneurysms has gained attention from physicians and engineers. Shear stresses, oscillatory shear index (OSI), gradient oscillatory number (GON), and residence time have been used as variables to describe the hemodynamics as well as the origin and evolution of aneurysms. However, the causes and hemodynamic conditions that promote their growth are still under debate. The present work presents numerical simulations of three types of aneurysms: two aortic and one cerebral. Simulation results showed that the blood rheology is not relevant for aortic aneurysms. However, for the cerebral aneurysm case, blood rheology could play a relevant role in the hemodynamics. The evaluated turbulence models showed equivalent results in both cases. Lastly, a simulation considering the fluid-structure interaction (FSI) showed that this phenomenon is the dominant factor for aneurysm simulation.

摘要

动脉瘤是一种血管畸形，可根据其位置（脑动脉瘤、主动脉瘤）或形状（囊状、梭形和霉菌性）进行分类。最近，血液流动与动脉瘤相互作用的研究引起了医生和工程师的关注。剪应力、振荡剪应力指数（OSI）、梯度振荡数（GON）和停留时间已被用作描述血流动力学以及动脉瘤的起源和演变的变量。然而，促进其生长的原因和血流动力学条件仍存在争议。目前的工作展示了三种类型动脉瘤的数值模拟：两个主动脉瘤和一个脑动脉瘤。模拟结果表明，血液流变学与主动脉瘤无关。然而，对于脑动脉瘤病例，血液流变学可能在血流动力学中发挥相关作用。评估的湍流模型在两种情况下显示出等效的结果。最后，考虑流固相互作用（FSI）的模拟表明，这种现象是动脉瘤模拟的主导因素。

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