Sundström Elias, Jiang Michael, Najm Hani K, Tretter Justin T
Department of Engineering Mechanics, FLOW Research Center, KTH Royal Institute of Technology, Teknikringen 8, 100 44 Stockholm, Sweden.
Department of Pediatric Cardiology, Cleveland Clinic, Cleveland, OH 44195, USA.
Bioengineering (Basel). 2023 Oct 12;10(10):1183. doi: 10.3390/bioengineering10101183.
This article presents the use of blood speckle Imaging (BSI) as an echocardiographic approach for the pre- and post-operative evaluation of subaortic membrane resection and aortic valve repair.
BSI, employing block-matching algorithms, provided detailed visualization of flow patterns and quantification of parameters from ultrasound data. The 9-year-old patient underwent subaortic membrane resection and peeling extensions of the membrane from under the ventricular-facing surface of all three aortic valve leaflets.
Post-operatively, BSI demonstrated improvements in hemodynamic patterns, where quantified changes in flow velocities showed no signs of stenosis and trivial regurgitation. The asymmetric jet with a shear layer and flow reversal on the posterior aspect of the aorta was corrected resulting in reduced wall shear stress on the anterior aspect and reduced oscillatory shear index, which is considered a contributing element in cellular alterations in the structure of the aortic wall.
This proof-of-concept study demonstrates the potential of BSI as an emerging echocardiographic approach for evaluating subaortic and aortic valvar repair. BSI enhances the quantitative evaluation of the left ventricular outflow tract of immediate surgical outcomes beyond traditional echocardiographic parameters and aids in post-operative decision-making. However, larger studies are needed to validate these findings and establish standardized protocols for clinical implementation.
本文介绍了利用血流散斑成像(BSI)作为一种超声心动图方法,用于主动脉瓣下隔膜切除术和主动脉瓣修复术前及术后的评估。
采用块匹配算法的BSI可对血流模式进行详细可视化,并从超声数据中对参数进行量化。该9岁患者接受了主动脉瓣下隔膜切除术,并从三个主动脉瓣叶心室面下方剥离了隔膜延伸部分。
术后,BSI显示血流动力学模式有所改善,流速的量化变化未显示狭窄迹象且仅有微量反流。主动脉后方具有剪切层和血流逆转的不对称射流得到纠正,导致主动脉前方的壁面剪应力降低,振荡剪切指数降低,而振荡剪切指数被认为是主动脉壁结构细胞改变的一个促成因素。
这项概念验证研究证明了BSI作为一种新兴的超声心动图方法在评估主动脉瓣下和主动脉瓣修复方面的潜力。BSI超越了传统超声心动图参数,增强了对左心室流出道即时手术结果的定量评估,并有助于术后决策。然而,需要更大规模的研究来验证这些发现,并建立临床实施的标准化方案。