Huang Zebin, Liu Shu, Nie Maodan, Yuan Jiabin, Lin Xumiao, Chu Xuerong, Shi Zhicai
Department of Orthopedics, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Bioengineering (Basel). 2023 Oct 16;10(10):1204. doi: 10.3390/bioengineering10101204.
A novel interlaminar elastic screw spacer technique was designed to maintain lumbar mobility in treating lumbar degenerative diseases. A validated finite element model of L4/5 was used to establish an ISES-1/2 model and an ISES-1/3 model based on different insertion points, a unilateral fixation model and a bilateral fixed model based on different fixation methods, and a Coflex-F model based on different implants. The elastic rods were used to fix screws. Under the same mechanical conditions, we compared the biomechanical characteristics to investigate the optimal entry point for ISES technology, demonstrate the effectiveness of unilateral fixation, and validate the feasibility of the ISES technique. Compared to ISES-1/3, the ISES-1/2 model had lower intradiscal pressure, facet cartilage stress, and posterior structural stress. Compared to the ISES-BF model, the ISES-UF model had lower intervertebral pressure, larger mobility, and smaller stress on the posterior structures. The ISES model had a similar intervertebral pressure and limitation of extension as the Coflex-F model. The ISES model retained greater mobility and reduced the stress on the facet cartilage and posterior structure compared with the Coflex-F model. Our study suggests that the ISES technique is a promising treatment of lumbar degenerative diseases, especially those with osteoporosis.
一种新型的层间弹性螺钉间隔器技术被设计用于在治疗腰椎退行性疾病时维持腰椎活动度。使用经过验证的L4/5有限元模型,基于不同的插入点建立ISES-1/2模型和ISES-1/3模型,基于不同的固定方法建立单侧固定模型和双侧固定模型,以及基于不同植入物建立Coflex-F模型。弹性杆用于固定螺钉。在相同的力学条件下,我们比较生物力学特性,以研究ISES技术的最佳进针点,证明单侧固定的有效性,并验证ISES技术的可行性。与ISES-1/3相比,ISES-1/2模型的椎间盘内压力、小关节软骨应力和后部结构应力更低。与ISES-BF模型相比,ISES-UF模型的椎间压力更低、活动度更大且后部结构应力更小。ISES模型的椎间压力和伸展限制与Coflex-F模型相似。与Coflex-F模型相比,ISES模型保留了更大的活动度,并降低了小关节软骨和后部结构的应力。我们的研究表明,ISES技术是治疗腰椎退行性疾病,尤其是骨质疏松症相关疾病的一种有前景的治疗方法。