Electronics and Telecommunications Department, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.
Automation and Electrical Engineering Department, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.
Sensors (Basel). 2024 Oct 12;24(20):6587. doi: 10.3390/s24206587.
This paper proposes an embedded Internet of Things (IoT) system for bioreactor sensor integration, aimed at optimizing temperature and turbidity control during cell cultivation. Utilizing an ESP32 development board, the system makes advances on previous iterations by incorporating superior analog-to-digital conversion capabilities, dual-core processing, and integrated Wi-Fi and Bluetooth connectivity. The key components include a DS18B20 digital temperature sensor, a TS-300B turbidity sensor, and a Peltier module for temperature regulation. Through real-time monitoring and data transmission to cloud platforms, the system facilitates advanced process control and optimization. The experimental results on yeast cultures demonstrate the system's effectiveness at maintaining optimal growth, highlighting its potential to enhance bioprocessing techniques. The proposed solution underscores the practical applications of the IoT in bioreactor environments, offering insights into the improved efficiency and reliability of culture cultivation processes.
本文提出了一种用于生物反应器传感器集成的嵌入式物联网 (IoT) 系统，旨在优化细胞培养过程中的温度和浊度控制。该系统利用 ESP32 开发板，通过集成更优的模数转换能力、双核处理以及集成的 Wi-Fi 和蓝牙连接功能，在之前的迭代基础上取得了进展。关键组件包括 DS18B20 数字温度传感器、TS-300B 浊度传感器以及用于温度调节的 Peltier 模块。通过实时监测和数据传输到云平台，该系统实现了先进的过程控制和优化。在酵母培养物上的实验结果表明，该系统能够有效地维持最佳生长，突出了其在增强生物加工技术方面的潜力。所提出的解决方案强调了物联网在生物反应器环境中的实际应用，为提高培养过程的效率和可靠性提供了新的见解。
