Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Gustav Mahlerlaan 3004, 1081 LA Amsterdam, The Netherlands.
Department of Periodontology, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Gustav Mahlerlaan 3004, 1081 LA Amsterdam, The Netherlands.
Molecules. 2023 Oct 19;28(20):7178. doi: 10.3390/molecules28207178.
Plant products have been employed in medicine for centuries. As the world becomes more health-conscious, there is a growing interest in natural and minimally processed products for oral health care. This has led to an increase in research into the bioactive compounds found in plant products, particularly monoterpenes. Monoterpenes are known to have beneficial biological properties, but the specific mechanisms by which they exert their effects are not yet fully understood. Despite this, some monoterpenes are already being used in oral health care. For example, thymol, which has antibacterial properties, is an ingredient in varnish used for caries prevention. In addition to this, monoterpenes have also demonstrated antifungal, antiviral, and anti-inflammatory properties, making them versatile for various applications. As research continues, there is potential for even more discoveries regarding the benefits of monoterpenes in oral health care. This narrative literature review gives an overview of the biological properties and current and potential applications of selected monoterpenes and their derivatives in oral health care. These compounds demonstrate promising potential for future medical development, and their applications in future research are expected to expand.
植物产品在医学领域已经应用了几个世纪。随着世界对健康的关注度不断提高,人们对天然和低加工产品在口腔保健方面的兴趣日益浓厚。这导致了对植物产品中生物活性化合物的研究不断增加,特别是单萜类化合物。已知单萜类化合物具有有益的生物学特性,但它们发挥作用的具体机制尚未完全了解。尽管如此,一些单萜类化合物已经在口腔保健中得到应用。例如,具有抗菌特性的百里酚是用于预防龋齿的清漆中的一种成分。除此之外,单萜类化合物还具有抗真菌、抗病毒和抗炎特性,因此在各种应用中具有多功能性。随着研究的继续,关于单萜类化合物在口腔保健中的益处,可能会有更多的发现。本综述性文献概述了选定的单萜类化合物及其衍生物在口腔保健中的生物学特性、当前和潜在的应用。这些化合物在未来的医学发展中具有很大的潜力,预计它们在未来研究中的应用将会扩大。